The comet assay is a versatile method to detect nuclear DNA damage in individual
eukaryotic cells, from yeast to human. The types of damage detected encompass DNA …

The comet assay is a widely used test for the detection of DNA damage and repair activity.
However, there are interlaboratory differences in reported levels of baseline and induced …

The present opinion deals with an updated safety assessment of the food additive titanium
dioxide (E 171) based on new relevant scientific evidence considered by the Panel to be …

The comet assay is a versatile method for measuring DNA strand breaks in individual cells. It
can also be applied to cells isolated from treated animals. In this review, we highlight …

This review discusses several research studies that employed comet assay to evaluate the
environmental impact of genotoxins in aquatic environments. It focuses on in vivo and in situ …

Oxidatively generated damage to DNA has been implicated in the pathogenesis of a wide
variety of diseases. Increasingly, interest is also focusing upon the effects of damage to the …

During the last 30 years, the comet assay has become widely used for the measurement of
DNA damage and repair in cells and tissues. A landmark achievement was reached in 2016 …

Carbon black exposure causes oxidative stress, inflammation and genotoxicity. The
objective of this systematic review was to assess the contributions of primary (ie direct …

The comet assay is widely used in studies on genotoxicity testing, human biomonitoring and
clinical studies. The simple version of the assay detects a mixture of DNA strand breaks and …

The comet assay (single cell gel electrophoresis) is widely used as a biomonitoring tool to
assess DNA damage–strand breaks, as well as oxidised bases; it can also be adapted to …