Sensorineural hearing loss (SNHL) can either be genetically inherited or acquired as a
result of aging, noise exposure, or ototoxic drugs. Although the precise pathophysiological …

Peritoneal dialysis (PD)-associated peritonitis is a serious complication of PD and
prevention and treatment of such is important in reducing patient morbidity and mortality …

Mitochondrial dysfunction is associated with the etiologies of sensorineural hearing loss,
such as age-related hearing loss, noise-and ototoxic drug-induced hearing loss, as well as …

Hearing disorders pose significant challenges to individuals experiencing them and their
overall quality of life, emphasizing the critical need for advanced pharmacological …

Background Ototoxicity is a severe side effect of aminoglycoside antibiotics.
Aminoglycosides are recommended for the treatment of multidrug-resistant TB (MDR-TB). N …

N-acetylcysteine (NAC) has shown beneficial effects in both acute and chronic kidney
disease in preclinical and clinical studies. Different dosage and administration forms of NAC …

Oxidative stress is a common feature of tuberculosis (TB), and persons with reduced
antioxidants are at more risk of TB. TB patients with relatively severe oxidative stress had …

Reactive oxygen species are important elements in ototoxic damage to hair cells (HCs),
appearing early in the damage process. Higher levels of natural antioxidants are positively …

Infection-related complications remain the most significant cause for morbidity and
technique failure in infants, children and adolescents who receive maintenance peritoneal …

Background The aim of the study is to evaluate the long-term protective effect of N-
acetylcysteine (NAC), an antioxidant agent, against aminoglycoside (AG)-induced …