The human microbiome constitutes a complex multikingdom community that symbiotically
interacts with the host across multiple body sites. Host-microbiome interactions impact …

Considerable progress has been made in recent years in the structural and molecular
biology of type IV secretion systems in Gram-negative bacteria. The latest advances have …

Type-A γ-aminobutyric (GABAA) receptors are ligand-gated chloride channels with a very
rich pharmacology. Some of their modulators, including benzodiazepines and general …

Gastric cancer constitutes one of the most prevalent malignancies in both sexes; it is
currently the fourth major cause of cancer-related deaths worldwide. The pathogenesis of …

Type A γ-aminobutyric acid (GABAA) receptors are pentameric ligand-gated ion channels
and the main drivers of fast inhibitory neurotransmission in the vertebrate nervous system …

Acinetobacter baumannii is regarded as a life-threatening pathogen associated with
community-acquired and nosocomial infections, mainly pneumonia. The rise in the number …

Type IV secretion systems (T4SSs) are versatile multiprotein nanomachines spanning the
entire cell envelope in Gram‐negative and Gram‐positive bacteria. They play important …

Chronic infection with Helicobacter pylori cagA-positive strains is the strongest risk factor for
gastric cancer. The cagA gene product, CagA, is delivered into gastric epithelial cells via the …

β-catenin/CTNNB1 is an intracellular scaffold protein that interacts with adhesion molecules
(E-cadherin/CDH1, N-cadherin/CDH2, VE-cadherin/CDH5 and α-catenins), transmembrane …

The efficacy of cancer immunotherapy largely depends on the tumor microenvironment,
especially the tumor immune microenvironment. Emerging studies have claimed that …