The application of mechanical forces to enable a chemical reaction, also known as
mechanochemistry, is actually experiencing an impressive renewal of interest among the …

A series of simple diarylhydrazide derivatives (45 examples) were well-designed, prepared,
and screened for their antifungal activities both in vitro and in vivo. Bioassay results …

N, N-Disubstituted hydrazides are useful synthetic building blocks and important
pharmaceutical scaffolds in the fields of organo-pharmaceutical chemistry. Direct C (O)–N–N …

A mechanochemical procedure was developed to obtain PZ-1361, a potent and selective 5-
HT7 receptor antagonist, with antidepressant properties in rodents. The elaborated protocol …

We present a PPh3/DDQ-mediated regiospecific selective N-functionalization of
arylhydrazines with primary benzylic alcohols and aryl carboxylic acids for the synthesis of N …

We herein describe a general approach to 5-trifluoromethyl 1, 2, 4-triazoles via the [3+ 2]-
cycloaddition of nitrile imines generated in situ from hydrazonyl chloride with CF3CN …

The use of ball-mills enabled the straightforward synthesis of a variety of silver (I) complexes
featuring challenging NHC ligands. Sterically hindered including electron-poor or with very …

Lithraea caustica (Molina) Hook. and Arn.(Anacardiaceae), common name Litre, is an
evergreen endemic plant used in the Mapuche Chilean folk medicine. The stem juice of L …

Acyl hydrazides are widely found in bioactive compounds and have important applications
as versatile synthetic intermediates. In the current report, a photoredox-catalyzed …

The development of efficient and environmentally friendly catalysts for the electro-oxidation
of hydrazine derivatives is of great importance in various industrial applications. In this study …