Surgery, chemotherapy, radiotherapy, and hormone therapy are the main common anti-
tumor therapeutic approaches. However, the non-specific targeting of cancer cells has made …

Hepatocyte resident afflictions continue to affect the human population unabated. The
asialoglycoprotein receptor (ASGPR) is primarily expressed on hepatocytes and minimally …

Curcumin is a promising therapeutic agent that exhibits manifold therapeutic activities.
However, it is challenging to study curcumin as it exhibits poor aqueous solubility and low …

Curcumin, a phenolic compound, possesses many pharmacological activities and is under
clinical evaluation to treat different diseases. However, conflicting data about its stability …

We report asialoglycoprotein receptor (ASGPR)-targeted doxorubicin hydrochloride (Dox)
nanoparticles (NPs) for hepatocellular carcinoma (HCC). Polyethylene sebacate (PES) …

Angelica sinensis polysaccharide (ASP) possesses diverse bioactivities; however, its
metabolic fate following oral administration remains poorly understood. To intuitively …

The journey against cancer has witnessed many trials to increase the safety and efficacy of
treatment. Zein is an excellent starting material for formulating nanosystems owing to its …

Safer and efficacious Amphotericin B (AmB) nanoformulations can be designed by
augmenting AmB in the monomeric or super-aggregated state, and restricting the …

This research addresses the development and in vitro evaluation of a microparticulate
system intended for intestine-targeted delivery of curcumin (CRM), a natural polyphenol with …

Targeted-drug administration to liver reduces side effects by minimising drug distribution to
non-target organs and increases therapeutic efficacy by boosting drug concentration in …