Humoral innate immunity and acute-phase proteins
A Mantovani, C Garlanda - New England Journal of Medicine, 2023 - Mass Medical Soc
Humoral Innate Immunity and Acute-Phase Proteins | New England Journal of Medicine Skip to
main content The New England Journal of Medicine homepage Advanced Search SEARCH …
main content The New England Journal of Medicine homepage Advanced Search SEARCH …
[HTML][HTML] Molecular insight into pentraxin-3: Update advances in innate immunity, inflammation, tissue remodeling, diseases, and drug role
Abstract Pentraxin-3 (PTX3) is the prototype of the long pentraxin subfamily, an acute-phase
protein consisting of a C-terminal pentraxin domain and a unique N-terminal domain. PTX3 …
protein consisting of a C-terminal pentraxin domain and a unique N-terminal domain. PTX3 …
[HTML][HTML] The immunopathogenesis of sarcoidosis
J Miedema, F Cinetto, A Smed-Sörensen… - Journal of …, 2024 - Elsevier
Sarcoidosis is a granulomatous multiorgan disease, thought to result from exposure to yet
unidentified antigens in genetically susceptible individuals. The exaggerated inflammatory …
unidentified antigens in genetically susceptible individuals. The exaggerated inflammatory …
Interplay between host humoral pattern recognition molecules controls undue immune responses against Aspergillus fumigatus
S Dellière, C Chauvin, SSW Wong, M Gressler… - Nature …, 2024 - nature.com
Abstract Pentraxin 3 (PTX3), a long pentraxin and a humoral pattern recognition molecule
(PRM), has been demonstrated to be protective against Aspergillus fumigatus, an airborne …
(PRM), has been demonstrated to be protective against Aspergillus fumigatus, an airborne …
Sarcoidosis and COVID-19: at the cross-road between immunopathology and clinical manifestation
Coronavirus disease 2019 (COVID-19) has been associated with dysregulation of the
immune system featuring inappropriate immune responses, exacerbation of inflammatory …
immune system featuring inappropriate immune responses, exacerbation of inflammatory …
The renin-angiotensin-aldosterone system regulates sarcoidosis granulomatous inflammation
Rationale: Sarcoidosis is a granulomatous disorder of unclear cause notable for abnormal
elevation of blood and tissue ACE1 (angiotensin converting enzyme 1) levels and activity …
elevation of blood and tissue ACE1 (angiotensin converting enzyme 1) levels and activity …
[HTML][HTML] PTX3 exacerbates hepatocyte pyroptosis in hepatic ischemia–reperfusion injury by promoting macrophage M1 polarization
P Jiang, L Luo, X Li, K Cai, S Chen, D Teng… - International …, 2024 - Elsevier
Backgrounds Hepatic ischemia–reperfusion injury (IRI) triggers macrophage activation,
which in turn mediates inflammatory responses and affects tissue repair and injury severity …
which in turn mediates inflammatory responses and affects tissue repair and injury severity …
Humoral pathways of innate immune regulation in granuloma formation
The humoral arm of mammalian innate immunity regulates several molecular mechanisms
involved in resistance to pathogens, inflammation, and tissue repair. Recent studies …
involved in resistance to pathogens, inflammation, and tissue repair. Recent studies …
Common clinical and molecular pathways between migraine and sarcoidosis
Migraine and sarcoidosis are two distinct medical conditions that may have some common
biological and clinical pathways. Sarcoidosis is a chronic granulomatous disease …
biological and clinical pathways. Sarcoidosis is a chronic granulomatous disease …
Metabolic regulation of the host–fungus interaction: from biological principles to therapeutic opportunities
Fungal infections present a significant global public health concern, impacting over 1 billion
individuals worldwide and resulting in more than 3 million deaths annually. Despite …
individuals worldwide and resulting in more than 3 million deaths annually. Despite …