The new antiepileptic drugs perampanel, retigabine, rufinamide and stiripentol were recently
approved for different epilepsy types. Being them an innovation in the antiepileptics …

Abstract Lennox-Gastaut Syndrome (LGS) is a rare form of childhood epilepsy. Rufinamide
is an orphan drug indicated for the treatment of LGS. Three-Dimensional Printing (3DP) is a …

Forced degradation studies of d-tubocurarine (DTC) was carried out in hydrolytic (acidic,
alkaline and neutral), thermal, photolytic and oxidative degradation conditions as per …

Objectives: Two optimized and validated high performance liquid chromatography (HPLC)
and spectrophotometric methods are proposed. The developed methods were quantified …

Rufinamide is an antiepileptic drug approved for seizures treatment associated with Lennox-
Gastaut syndrome. To support future pharmacokinetic studies in rodents, this work aimed to …

Abstract Rufinamide (RF), antiepileptic drug, is biotransformed to inactive metabolite.
Frequent plasma monitoring is required for dose adjustment. This work is concerned with the …

ABSTRACT Objective: Lennox–Gastaut syndrome (LGS) is mainly treated with antiepileptic
drugs (AEDs) but using one AED is not sufficient to relieve all or even most patients. A …

Abstract Pregabalin, Lacosamide, Rufinamide, Perampanel, Eslicarbazepine acetate,
Brivaracetam, Cannabidiol, Stiripentol, Everolimus, Cenobamate, and Fenfluramine are …

Rufinamide is a third-generation, a triazole derivative drug. Rufinamide is indicated for
treatment of seizures associated with Lennox-Gastaut syndrome (LGS). LGS is one of the …

ABSTRACT INTRODUCTION: Objectives: Two optimized and validated HPLC and
spectrophotometric methods were proposed. The developed methods were quantified with …