Childhood brain tumors are the most common pediatric solid tumor and include several
histologic subtypes. Although progress has been made in improving survival rates for some …

Atypical teratoid/rhabdoid tumor (AT/RT) is the most common malignant CNS tumor of
children below 6 months of age. The majority of AT/RTs demonstrate genomic alterations in …

PURPOSE Atypical teratoid/rhabdoid tumor (AT/RT) is an aggressive, early-childhood brain
tumor without standard effective treatment. To our knowledge, we conducted the first AT/RT …

We recently reported that atypical teratoid rhabdoid tumors (ATRTs) comprise at least two
transcriptional subtypes with different clinical outcomes; however, the mechanisms …

Pediatric neuro-oncology has undergone an exciting and dramatic transformation during the
past 5 years. This article summarizes data from collaborative group and institutional trials …

Medulloblastoma, the most common malignant paediatric brain tumour, is currently
diagnosed and stratified using a combination of clinical and demographic variables. Recent …

Background Controversy exists as to what may be defined as standard of care (including
markers for stratification) for patients with atypical teratoid/rhabdoid tumors (ATRTs). The …

Background Rhabdoid brain tumours, also called atypical teratoid rhabdoid tumours, are
lethal childhood cancers with characteristic genetic alterations of SMARCB1/hSNF5. Lack of …

Atypical teratoid rhabdoid tumors (ATRTs) are rare central nervous system tumors that
comprise approximately 1–2% of all pediatric brain tumors; however, in patients less than 3 …

Central nervous system (CNS) tumors are the most common solid tumor in pediatrics,
accounting for approximately 25% of all childhood cancers, and the second most common …