Allergic diseases such as allergic rhinitis (AR), allergic asthma (AAS), atopic dermatitis (AD),
food allergy (FA), and eczema are systemic diseases caused by an impaired immune …

Pruritus is a common symptom of several skin diseases, both inflammatory and neoplastic.
Pruritus might have a tremendous impact on patients' quality of life and strongly interfere …

Background Tralokinumab is a fully human monoclonal antibody that specifically neutralizes
interleukin‐13, a key driver of atopic dermatitis (AD). Objectives To evaluate the efficacy and …

Alterations in the gut microbiome, including diet-driven changes, are linked to the rising
prevalence of food allergy. However, little is known about how specific gut bacteria trigger …

Hidradenitis suppurativa (HS) is a debilitating chronic inflammatory skin disease
characterized by chronic abscess formation and development of multiple draining sinus …

Macrophage plasticity is critical for normal tissue repair following injury. In pathologic states
such as diabetes, macrophage plasticity is impaired, and macrophages remain in a …

Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases, which
generally presents with intense itching and recurrent eczematous lesions. AD affects up to …

The IL-36 family of cytokines includes three pro-inflammatory agonists (IL-36α, IL-36β, and
IL-36γ) and a receptor antagonist (IL-36Ra), which bind and signal through a heterodimeric …

Background Skin transcriptome studies in atopic dermatitis (AD) showed broad
dysregulation as well as “improvement” under therapy. These observations were mainly …

Atopic dermatitis (AD) is one of the most prevalent inflammatory disease among non-fatal
skin diseases, affecting up to one fifth of the population in developed countries. AD is …