Alcohol induces p53-mediated apoptosis in neural crest by stimulating an AMPK-mediated suppression of TORC1, S6K, and ribosomal biogenesis

Y Huang, GR Flentke, SM Smith - Reproductive Toxicology, 2024 - Elsevier
Prenatal alcohol exposure is a leading cause of permanent neurodevelopmental disability
and can feature distinctive craniofacial deficits that partly originate from the apoptotic …

Influence of Gut Microbiota and its Metabolites on Progression of Metabolic Associated Fatty Liver Disease

YY Wang, HL Lin, KL Wang, GX Que, T Cao… - Chinese Medical …, 2023 - Elsevier
Metabolic associated fatty liver disease (MAFLD) has become a prevalent chronic liver
disease worldwide because of lifestyle and dietary changes. Gut microbiota and its …

刺梨渣多酚对高脂膳食小鼠脂代谢及其诱发的氧化应激的影响.

安玉红, 朱德星, 胡文森… - Food Research & …, 2022 - search.ebscohost.com
为了探讨刺梨渣多酚对高脂膳食小鼠脂代谢及其诱发的氧化应激的影响, 将小鼠分为空白组,
模型组以及刺梨渣多酚低, 中, 高剂量组[50,100,200 mg/(kg bw)], 实验时间60 d. 实验结束后 …

Effects of metformin on binge‐like ethanol drinking and adenosine monophosphate kinase signaling in inbred high drinking in the dark line 1 mice

K Grigsby, J Palacios, AE Chan… - Alcohol: Clinical and …, 2024 - Wiley Online Library
Background Adenosine monophosphate‐activated protein kinase (AMPK) signaling plays a
vital role in regulating cellular metabolism and energy throughout the body. Ethanol and …

Region-specific alterations in the expression and phosphorylation of NMDA receptor subunits in the rat prefrontal cortex and dorsal striatum accompanying behavioral …

S Xu, UG Kang - Pharmacology Biochemistry and Behavior, 2024 - Elsevier
Behavioral sensitization is defined as the enhanced behavioral response to drugs of abuse
after repeated exposure, which can serve as a behavioral model of addiction. Our previous …

[HTML][HTML] 肠道微生物及其代谢产物对代谢相关性脂肪肝病发生发展的影响

汪远远, 林海连, 王克浪, 曹婷, 朱腊梅, 杨霞… - 中国医学科学杂志 …, 2024 - cmsj.cams.cn
由于生活方式和饮食习惯的改变, 代谢相关性脂肪肝已成为全球流行的慢性肝病. 研究表明:
肠道微生物群及其代谢产物在代谢相关性脂肪肝的发病机制中起着至关重要的作用 …