Lignans are found in a wide variety of plant species. The lignan podophyllotoxin is of special
interest, since its derivatives like eg etopophos® are used in anticancer therapy. As …

The natural lignan podophyllotoxin, a dimerized product of two phenylpropanoid moieties
which occurs in a few plant species, is a pharmacologically important compound for its …

Cytotoxic lignans derived from podophyllotoxin are currently used in cancer chemotherapy.
Podophyllotoxin for semi-synthetic derivatization is isolated from the rhizomes of …

Medicinal plants are the most promising source for the development of drugs, and many
types of active ingredients from the plant resources have been studied in order to clarify the …

The genus Linum includes more than 230 globally distributed species, which have attracted
great interest as they grow rapidly and are already sources of commercially important …

Abstract A combined HPLC‐UV/PAD and HPLC‐ESI/MS method allowing the fast detection
and identification/structural characterisation of lignans of different structural subclasses is …

Secondary metabolites from numerous plant sources have been developed as anti-cancer
reagents and compounds such as resveratrol, podophyllotoxin and zerumbone are of …

The genus Linum consists of about 200 species of annual or perennial herbs or subshrubs.
Most of our knowledge of the chemical constituents of members of the genus is limited to far …

Novel cross‐species coculture systems using Linum flavumhairy roots and Podophyllum
hexandrum cell suspensions were applied for in vitro production of podophyllotoxin. The …

Cell-suspension cultures of Linum flavum L.(Linaceae) synthesize and accumulate
aryltetrahydronaphthalene lignans with 6-methoxypodophyllotoxin as the main component …