Insertions and deletions constitute the second most important source of natural genomic
variation. Insertions and deletions make up to 25% of genomic variants in humans and are …

Highlights•New plant viruses diseases emerge periodically in crops.•These viruses jump
species from other crops, or from wild plants.•The role of biodiversity loss, or ecosystem …

Motivation: We present a new feature of the MAFFT multiple alignment program for
suppressing over-alignment (aligning unrelated segments). Conventional MAFFT is highly …

What are the models used in phylogenetic analysis and what exactly is involved in Bayesian
evolutionary analysis using Markov chain Monte Carlo (MCMC) methods? How can you …

Research aimed at understanding the geographic context of evolutionary histories is
burgeoning across biological disciplines. Recent endeavors attempt to interpret …

With early life likely to have existed in a hot environment, enzymes had to cope with an
inherent drop in catalytic speed caused by lowered temperature. Here we characterize the …

The statistical methods applied to the analysis of genomic data do not account for
uncertainty in the sequence alignment. Indeed, the alignment is treated as an observation …

Behavioural responses to temperature are critical for survival, and animals from insects to
humans show strong preferences for specific temperatures,. Preferred temperature selection …

Previous molecular analyses of higher hymenopteran relationships have largely been
based on subjectively aligned ribosomal sequences (18S and 28S). Here, we reanalyze the …

Burkholderia multivorans is an opportunistic pathogen capable of causing severe disease in
patients with cystic fibrosis (CF). Patients may be chronically infected for years, during which …