Synergy and antagonism in natural product extracts: when 1+ 1 does not equal 2

LK Caesar, NB Cech - Natural product reports, 2019 - pubs.rsc.org
Covering: 2000 to 2019 According to a 2012 survey from the Centers for Disease Control
and Prevention, approximately 18% of the US population uses natural products (including …

Pharmacological properties of melanin and its function in health

AS ElObeid, A Kamal‐Eldin… - Basic & clinical …, 2017 - Wiley Online Library
The biological pigment melanin is present in most of the biological systems. It manifests a
host of biological and pharmacological properties. Its role as a molecule with special …

Characteristics and immune-enhancing activity of pectic polysaccharides from sweet cherry (Prunus avium)

J Cao, D Tang, Y Wang, X Li, L Hong, C Sun - Food Chemistry, 2018 - Elsevier
Two water soluble polysaccharides components PAPS-1 and PAPS-2 with homogeneously
distributed molecular weight were obtained from Prunus avium. PAPS-1 and PAPS-2 …

Morphological, physiological, cytological and phytochemical studies in diploid and colchicine-induced tetraploid plants of Echinacea purpurea (L.)

M Abdoli, A Moieni, H Naghdi Badi - Acta physiologiae plantarum, 2013 - Springer
Echinacea purpurea (L.) is one of the important medicinal plant species. To obtain the
tetraploid plants of Echinacea purpurea with improved medicinal qualities, the root tips of …

Panax quinquefolius (North American Ginseng) Polysaccharides as Immunomodulators: Current Research Status and Future Directions

R Ghosh, DL Bryant, AL Farone - Molecules, 2020 - mdpi.com
Panax quinquefolius (North American ginseng, NAG) is a popular medicinal plant used
widely in traditional medicine. NAG products are currently available in various forms such as …

Ethanolic Echinacea purpurea Extracts Contain a Mixture of Cytokine-Suppressive and Cytokine-Inducing Compounds, Including Some That Originate from …

DA Todd, TV Gulledge, ER Britton, M Oberhofer… - PloS one, 2015 - journals.plos.org
Echinacea preparations, which are used for the prevention and treatment of upper
respiratory infections, account for 10% of the dietary supplement market in the US, with sales …

Analytical methods for the study of bioactive compounds from medicinally used Echinacea species

R Bruni, V Brighenti, LK Caesar, D Bertelli… - … of pharmaceutical and …, 2018 - Elsevier
Abstract Echinacea purpurea (L.) Moench, Echinacea angustifolia DC. var. angustifolia and
Echinacea pallida (Nutt.) Nutt. are frequently used as medicinal plants and their …

Polysaccharides isolated from Acai fruit induce innate immune responses

J Holderness, IA Schepetkin, B Freedman… - PloS one, 2011 - journals.plos.org
The Açaí (Acai) fruit is a popular nutritional supplement that purportedly enhances immune
system function. These anecdotal claims are supported by limited studies describing …

Fungal polysaccharides from Inonotus obliquus are agonists for Toll-like receptors and induce macrophage anti-cancer activity

CW Wold, PF Christopoulos, MA Arias… - Communications …, 2024 - nature.com
Fungal polysaccharides can exert immunomodulating activity by triggering pattern
recognition receptors (PRRs) on innate immune cells such as macrophages. Here, we …

Mast cell degranulation and calcium influx are inhibited by an Echinacea purpurea extract and the alkylamide dodeca-2E, 4E-dienoic acid isobutylamide

TV Gulledge, NM Collette, E Mackey… - Journal of …, 2018 - Elsevier
Abstract Ethnopharmacological relevance Native Americans used plants from the genus
Echinacea to treat a variety of different inflammatory conditions including swollen gums, sore …