After nearly four decades of research, a safe and effective HIV-1 vaccine remains elusive.
There are many reasons why the development of a potent and durable HIV-1 vaccine is …

The global emergence of many severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) variants jeopardizes the protective antiviral immunity induced after infection or …

Background A safe, effective vaccine is essential to eradicating human immunodeficiency
virus (HIV) infection. A canarypox–protein HIV vaccine regimen (ALVAC-HIV plus AIDSVAX …

Development of an efficacious HIV‐1 vaccine is a major priority for improving human health
worldwide. Vaccine‐mediated protection against human pathogens can be achieved …

An efficacious HIV-1 vaccine is regarded as the best way to halt the ongoing HIV-1
epidemic. However, despite significant efforts to develop a safe and effective vaccine, the …

Today, vaccinologists have come to understand that the hallmark of any protective immune
response is the antigen. However, it is not the whole antigen that dictates the immune …

One of the most successful HIV vaccines to date, the RV144 vaccine tested in Thailand,
demonstrated correlates of protection including cross-clade V1V2 immunoglobulin G (IgG) …

This systematic review was undertaken to determine the extent to which adult subjects
representing sex (female), race (nonwhite), and age (> 50 years) categories are included in …

Vaccine efficacy determined within the controlled environment of a clinical trial is usually
substantially greater than real-world vaccine effectiveness. Typically, this results from …

Clinical immunogenetics laboratories performing routine sequencing of human leukocyte
antigen (HLA) genes in support of hematopoietic cell transplantation are motivated to …