The microbiota–gut–brain axis and Alzheimer's disease: neuroinflammation is to blame?

A Megur, D Baltriukienė, V Bukelskienė, A Burokas - Nutrients, 2020 - mdpi.com
For years, it has been reported that Alzheimer's disease (AD) is the most common cause of
dementia. Various external and internal factors may contribute to the early onset of AD. This …

The gut microbiome alterations and inflammation-driven pathogenesis of Alzheimer's disease—a critical review

M Sochocka, K Donskow-Łysoniewska, BS Diniz… - Molecular …, 2019 - Springer
One of the most important scientific discoveries of recent years was the disclosure that the
intestinal microflora takes part in bidirectional communication between the gut and the brain …

Modified Mediterranean-ketogenic diet modulates gut microbiome and short-chain fatty acids in association with Alzheimer's disease markers in subjects with mild …

R Nagpal, BJ Neth, S Wang, S Craft, H Yadav - EBioMedicine, 2019 - thelancet.com
Background Alzheimer's disease (AD) prevalence is increasing, but its etiology remains
elusive. Gut microbes can contribute to AD pathology and may help identifying novel …

Gut mycobiome and its interaction with diet, gut bacteria and alzheimer's disease markers in subjects with mild cognitive impairment: A pilot study

R Nagpal, BJ Neth, S Wang, SP Mishra, S Craft… - …, 2020 - thelancet.com
Background Recently, we reported that patients with mild cognitive impairment (MCI) harbor
specific signature of bacteria in their gut and that a modified Mediterranean ketogenic diet …

Sodium butyrate ameliorates the impairment of synaptic plasticity by inhibiting the neuroinflammation in 5XFAD mice

Y Jiang, K Li, X Li, L Xu, Z Yang - Chemico-biological interactions, 2021 - Elsevier
Current strategies for the treatment of Alzheimer's disease (AD) focus on the pathology in the
later stages of disease progression. Early microglia abnormality and β-amyloid (Aβ) …

The contribution of gut microbiota–brain axis in the development of brain disorders

J Maiuolo, M Gliozzi, V Musolino, C Carresi… - Frontiers in …, 2021 - frontiersin.org
Different bacterial families colonize most mucosal tissues in the human organism such as
the skin, mouth, vagina, respiratory, and gastrointestinal districts. In particular, the …

[HTML][HTML] The relationship between stress and Alzheimer's disease

NJ Justice - Neurobiology of stress, 2018 - Elsevier
Stress is critically involved in the development and progression of disease. From the stress
of undergoing treatments to facing your own mortality, the physiological processes that …

Nanoformulations of herbal extracts in treatment of neurodegenerative disorders

SZ Moradi, S Momtaz, Z Bayrami… - … in bioengineering and …, 2020 - frontiersin.org
Nanotechnology is one of the methods that influenced human life in different ways and is a
substantial approach that assists to overcome the multiple limitations of various diseases …

Gut microbiota in Alzheimer's disease, depression, and type 2 diabetes mellitus: The role of oxidative stress

M Luca, M Di Mauro, M Di Mauro… - Oxidative medicine and …, 2019 - Wiley Online Library
Gut microbiota consists of over 100 trillion microorganisms including at least 1000 different
species of bacteria and is crucially involved in physiological and pathophysiological …

Epigallocatechin‐3‐gallate attenuates microglial inflammation and neurotoxicity by suppressing the activation of canonical and noncanonical inflammasome via TLR4 …

X Zhong, M Liu, W Yao, K Du, M He… - Molecular nutrition & …, 2019 - Wiley Online Library
Scope In this study, it has been investigated whether the neuroprotective efficacy of
epigallocatechin‐3‐gallate (EGCG) is mediated by inhibition of canonical and noncanonical …