Decline in biological resilience (ability to recover) is a key manifestation of aging that
contributes to increase in vulnerability to death with age eventually limiting longevity even in …

Chronic health conditions are commonplace in older populations. The process of aging
impacts many of the world's top health concerns. With the average life expectancy …

Inverse comorbidity is a lower-than-expected probability of disease occuring in individuals
who have been diagnosed with other medical conditions. Emerging evidence points to …

In the past 5 years, several leading groups have attempted to explain why individuals with
Down's syndrome have a reduced risk of many solid tumours and an increased risk of …

Life expectancy has dramatically expanded, the global population has aged
unprecedentedly and the number of centenarians has significantly increased. The analysis …

When we think of the forces driving cancer, we don't necessarily think of evolution. But
evolution and cancer are closely linked because the historical processes that created life …

Complex diseases are major contributors to human mortality in old age. Paradoxically, many
genetic variants that have been associated with increased risks of such diseases are found …

Epidemiological cancer data shed light on key questions within basic science, clinical
medicine and public health. For decades, Denmark has had linkable health registers that …

Despite evident success in clarifying many important features of Alzheimer's disease (AD)
the efficient methods of its prevention and treatment are not yet available. The reasons are …

Different cell types within the body exhibit substantial variation in the average time they live,
ranging from days to the lifetime of the organism. The underlying mechanisms governing the …