There are few tumor cell subpopulations with stem cell characteristics in tumor tissue,
defined as cancer stem cells (CSCs) or cancer stem-like cells (CSLCs), which can …

The properties of cancer stem cells (CSCs), such as self-renewal, drug resistance, and
metastasis, have been indicated to be responsible for the poor prognosis of patients with …

Cancer is one of the deadliest diseases in the world. Despite extensive studies, treating
metastatic cancers remains challenging. Years of research have linked a rare set of cells …

MicroRNAs (miRNAs) constitute a class of short non coding RNAs that have crucial
biological roles by acting mainly as negative regulators of gene expression. The alteration of …

Background Metastasis remains one of the greatest challenges involved in treating gastric
cancer (GC). Ropivacaine (Rop) is not only a well-documented local anesthetic medicament …

MicroRNAs (miRNAs or miRs) have a critical role in regulating stem cells (SCs) during
development and altered expression can cause developmental defects and/or disease …

Recent accumulating researches implicate that non-coding RNAs (ncRNAs) including
microRNA (miRNA), circular RNA (circRNA), and long non-coding RNA (lncRNAs) play …

APC mutations drive human colorectal cancer (CRC) development. A major contributing
factor is colonic stem cell (SC) overpopulation. But, the mechanism has not been fully …

The anti-cancer effect of retinoic acid signaling in CRC occurs via decreased growth of ALDH+
colon cancer stem cells and increased differentiation of stem cells - PMC Back to Top Skip to …

The chromatin-associated high mobility group protein N2 (HMGN2) cofactor regulates
transcription factor activity through both chromatin and protein interactions. Hmgn2 …