Brain interictal epileptiform discharges (IEDs), as one of the hallmarks of epileptic brain, are
transient events captured by electroencephalogram (EEG). IEDs are generated by seizure …

We directly assessed mesial temporal activity using intracranial foramen ovale electrodes in
two patients with Alzheimer's disease (AD) without a history or EEG evidence of seizures …

Many patients with medically refractory epilepsy now undergo successful surgery based on
noninvasive diagnostic information, but intracranial electroencephalography (IEEG) …

Cortical network hyperexcitability is an inextricable feature of Alzheimer's disease (AD) that
also might accelerate its progression. Seizures are reported in 10–22% of patients with AD …

Objective Develop a high-performing algorithm to detect mesial temporal lobe (mTL)
epileptiform discharges on intracranial electrode recordings. Methods An epileptologist …

Importance The hippocampus is a highly epileptogenic brain region, yet over 90% of
hippocampal epileptiform activity (HEA) cannot be identified on scalp electroencephalogram …

Both sleep alterations and epileptiform activity are associated with the accumulation of
amyloid-β and tau pathology and are currently investigated for potential therapeutic …

Background and Objectives To investigate the spatiotemporal characteristics of sleep
waveforms in temporal lobe epilepsy (TLE) and examine their association with cognition …

Electroencephalogram (EEG) plays a pivotal role in the detection and analysis of epileptic
seizures, which affects over 70 million people in the world. Nonetheless, the visual …

BACKGROUND: The recently developed magnetic resonance imaging–guided laser-
induced thermal therapy offers a minimally invasive alternative to craniotomies performed for …