Proteomic Analyses Reveal the Role of Alpha-2-Macroglobulin in Canine Osteosarcoma Cell Migration

SS Wilk, K Michalak, EP Owczarek… - International Journal of …, 2024 - mdpi.com
Canine osteosarcoma (OSA) is an aggressive bone neoplasia with high metastatic potential.
Metastasis is the main cause of death associated with OSA, and there is no current treatment …

Structural characterization of complex tannins from Euryale ferox fruit peels and their inhibitory mechanisms against tyrosinase activity and melanogenesis

L Wu, W Song, Y Jiang, Y Dai, Z Qin, L Liu… - International Journal of …, 2025 - Elsevier
Tyrosinase is a rate-limiting enzyme for melanogenesis and abnormal melanin production
can be controlled by utilizing tyrosinase inhibitory substances. To develop potent and safe …

Alpha-2-Macroglobulin Is a Novel Anticancer Agent

F Facchiano, D D'Arcangelo, A Facchiano - Oncology, 2024 - karger.com
Introduction: Melanoma is the most aggressive skin cancer, with an increasing occurrence.
Despite the recent important improvements due to novel immunotherapy approaches, when …

Alpha-2-Macroglobulin Is a Novel Anticancer Agent

FFD DLArcangelob, A Facchianob - 2023 - karger.com
Introduction: Melanoma is the most aggressive skin cancer, with an increasing occurrence.
Despite the recent important improvements due to novel immunotherapy approaches, when …