Accessible and adaptable multiplexed real-time PCR approaches to identify SARS-CoV-2 variants of concern

T Yan, Y Xu, R Zheng, X Zeng, Z Chen, S Lin… - Microbiology …, 2022 - Am Soc Microbiol
Rapid identification and continuous surveillance of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) variants are critical for guiding the response to the COVID-19 …

Comparative analysis of five multiplex RT-PCR assays in the screening of SARS-CoV-2 variants

V De Pace, B Bruzzone, A Orsi, V Ricucci, A Domnich… - Microorganisms, 2022 - mdpi.com
The rapid and presumptive detection of SARS-CoV-2 variants may be performed using
multiplex RT-PCR assays. The aim of this study was to evaluate the diagnostic performance …

Multiplex fragment analysis for flexible detection of all SARS-CoV-2 variants of concern

AE Clark, Z Wang, E Ostman, H Zheng, H Yao… - Clinical …, 2022 - academic.oup.com
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
continue to emerge, and effective tracking requires rapid return of results. Surveillance of …

Evaluation of the clinical and analytical performance of the Seegene allplex™ SARS-CoV-2 variants I assay for the detection of variants of concern (VOC) and variants …

M Caza, CA Hogan, A Jassem, N Prystajecky… - Journal of Clinical …, 2021 - Elsevier
Background High-throughput assays for the detection of SARS-CoV-2 variants of concern
(VOC) and interest (VOI) are a diagnostic alternative when whole genome sequencing …

SARS-CoV-2 Mutations and Variants: what do we know so far?

S Pecho-Silva, JJ Barboza… - Microbes, Infection …, 2021 - revistas.unheval.edu.pe
With the circulation of the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2)
variants of concern (VOC), there is a worry that an increase in transmission, hospitalisations …

Genomic epidemiology and serology associated with a SARS-CoV-2 R. 1 variant outbreak in New Jersey

B Mathema, L Chen, P Wang, MH Cunningham… - MBio, 2022 - Am Soc Microbiol
Examining the neutralizing capacity of monoclonal antibodies (MAbs) used to treat COVID-
19, as well as antibodies recovered from unvaccinated, previously vaccinated, and infected …

Inadequate design of mutation detection panels prevents interpretation of variants of concern: results of an external quality assessment for SARS-CoV-2 variant …

C Buchta, JV Camp, J Jovanovic, U Radler… - Clinical Chemistry and …, 2022 - degruyter.com
Objectives Mutation-specific PCR assays have quickly found their way into laboratory
diagnostics due to their capacity to be a fast, easy to implement and high-throughput method …

Molecular and clinical epidemiology of SARS-CoV-2 infection among vaccinated and unvaccinated individuals in a large healthcare organization from New Jersey

JR Mediavilla, T Lozy, A Lee, J Kim, VW Kan, E Titova… - Viruses, 2023 - mdpi.com
New Jersey was among the first states impacted by the COVID-19 pandemic, with one of the
highest overall death rates in the nation. Nevertheless, relatively few reports have been …

Epidemiological Insights into the Omicron Outbreak via MeltArray-Assisted Real-Time Tracking of SARS-CoV-2 Variants

T Yan, R Zheng, Y Li, S Sun, X Zeng, Z Yue, Y Liao… - Viruses, 2023 - mdpi.com
The prolonged course of the COVID-19 pandemic necessitates sustained surveillance of
emerging variants. This study aimed to develop a multiplex real-time polymerase chain …

Identification of genotypic variants and its proteomic mutations of Brazilian Sars-Cov-2 isolates

R Prathiviraj, P Chellapandi, A Begum, GS Kiran… - Virus research, 2022 - Elsevier
The second wave of COVID-19 caused by severe acute respiratory syndrome virus (SARS-
CoV-2) is rapidly spreading over the world. Mechanisms behind the flee from current …