Metal micronutrients are essential for life and exist in a delicate balance to maintain an
organism's health. The labile nature of metal–biomolecule interactions clouds the …

Ferritin may serve as a nanocarrier for the selective delivery of anticancer metallodrugs.
Here, we have prepared and characterized a well-defined conjugate between the gold drug …

Aurothiomalate (AuTM) is an FDA‐approved antiarthritic gold drug with unique anticancer
properties. To enhance its anticancer activity, we prepared a bioconjugate with human …

Herein we describe a method for the efficient production (∼ 90% fluorination) of 5-F-Trp
human H ferritin via the selective incorporation of 19 F into the side chain of W93 using 5 …

Solution interactions of three organomercury compounds, ie, methylmercury chloride,
thimerosal and phenylmercury acetate, with a group of biochemically relevant proteins …

Many efforts have been made in the last few decades to selectively transport antitumor
agents to their potential target sites with the aim to improve efficacy and selectivity. Indeed …

An imbalance in iron homeostasis contributes to mitochondrial dysfunction, which is closely
linked to the pathogenesis of various diseases. Herein, we developed a nanosensor for …

The iron core of Escherichia coli ferritin was reconstituted in the presence and absence of
phosphate. The core formed in the presence of phosphate contained phosphate in amounts …

The role of solvent‐exposed cysteines as reactive sites for bioconjugation with a variety of
metal drugs or fluorescent probes is emerging in the use of human H‐ferritin (HuHf) as a …

Trypanothione reductase from Trypanosoma brucei (TbTR) is a key enzyme of the parasite
responsible for human African trypanosomiasis. TbTR catalyzes the reduction of …