Epitopes in the HA and NA of H5 and H7 avian influenza viruses that are important for antigenic drift

JM Luczo, E Spackman - FEMS Microbiology Reviews, 2024 - academic.oup.com
Avian influenza viruses evolve antigenically to evade host immunity. Two influenza A virus
surface glycoproteins, the haemagglutinin and neuraminidase, are the major targets of host …

Non-mouse-adapted H1N1pdm09 virus as a model for influenza research

I Kiseleva, A Rekstin, M Al Farroukh, E Bazhenova… - Viruses, 2020 - mdpi.com
The number of lung-adapted influenza viruses is limited. Most of them are not antigenically
related to current circulating viruses. Viruses similar to recent strains are required for …

The evolution of hemagglutinin-158 and neuraminidase-88 glycosylation sites modulates antigenicity and pathogenicity of clade 2.3. 2.1 H5N1 avian influenza viruses

N Xu, Y Chen, Y Wu, Y Guo, C Wang, T Qin… - Veterinary …, 2025 - Elsevier
Abstract Clade 2.3. 2.1 of the H5N1 avian influenza virus (AIV) evolved into several
subclades. However, the effect of glycosylation on the biological characteristics of …

Engineering an optimal Y280-lineage H9N2 vaccine strain by tuning PB2 activity

SH An, SM Hong, JH Song, SE Son, CY Lee… - International Journal of …, 2023 - mdpi.com
H9N2 avian influenza A viruses (AIVs) cause economic losses in the poultry industry and
provide internal genomic segments for the evolution of H5N1 and H7N9 AIVs into more …

[HTML][HTML] A Model H5N2 Vaccine Strain for Dual Protection Against H5N1 and H9N2 Avian Influenza Viruses

JH Song, SE Son, HW Kim, SH An, CY Lee, HJ Kwon… - Vaccines, 2024 - mdpi.com
Background/Objective: Highly pathogenic (HP) H5Nx and low-pathogenicity (LP) H9N2
avian influenza viruses (AIVs) pose global threats to the poultry industry and public health …

Selection of an optimal recombinant egyptian H9N2 avian influenza vaccine strain for poultry with high antigenicity and safety

SH An, SE Son, JH Song, SM Hong, CY Lee, NH Lee… - Vaccines, 2022 - mdpi.com
For the development of an optimized Egyptian H9N2 vaccine candidate virus for poultry,
various recombinant Egyptian H9N2 viruses generated by a PR8-based reverse genetics …