Imaging challenges in biomaterials and tissue engineering

AA Appel, MA Anastasio, JC Larson, EM Brey - Biomaterials, 2013 - Elsevier
Biomaterials are employed in the fields of tissue engineering and regenerative medicine
(TERM) in order to enhance the regeneration or replacement of tissue function and/or …

The role of machine learning and design of experiments in the advancement of biomaterial and tissue engineering research

G Al-Kharusi, NJ Dunne, S Little, TJ Levingstone - Bioengineering, 2022 - mdpi.com
Optimisation of tissue engineering (TE) processes requires models that can identify
relationships between the parameters to be optimised and predict structural and …

Early T2 changes predict onset of radiographic knee osteoarthritis: data from the osteoarthritis initiative

H Liebl, G Joseph, MC Nevitt, N Singh… - Annals of the rheumatic …, 2015 - Elsevier
Objective To evaluate whether T2 relaxation time measurements obtained at 3 T MRI predict
the onset of radiographic knee osteoarthritis (OA). Materials and methods We performed a …

Machine learning prediction of collagen fiber orientation and proteoglycan content from multiparametric quantitative MRI in articular cartilage

SA Mirmojarabian, AW Kajabi… - Journal of Magnetic …, 2023 - Wiley Online Library
Background Machine learning models trained with multiparametric quantitative MRIs
(qMRIs) have the potential to provide valuable information about the structural composition …

Monitoring cartilage tissue engineering using magnetic resonance spectroscopy, imaging, and elastography

M Kotecha, D Klatt, RL Magin - Tissue Engineering Part B: Reviews, 2013 - liebertpub.com
A key technical challenge in cartilage tissue engineering is the development of a
noninvasive method for monitoring the composition, structure, and function of the tissue at …

[HTML][HTML] Machine learning classification of OARSI-scored human articular cartilage using magnetic resonance imaging

BG Ashinsky, CE Coletta, M Bouhrara, VA Lukas… - Osteoarthritis and …, 2015 - Elsevier
Objective The purpose of this study is to evaluate the ability of machine learning to
discriminate between magnetic resonance images (MRI) of normal and pathological human …

Applications of computer modeling and simulation in cartilage tissue engineering

D Pearce, S Fischer, F Huda, A Vahdati - Tissue engineering and …, 2020 - Springer
Background: Advances in cartilage tissue engineering have demonstrated noteworthy
potential for developing cartilage for implantation onto sites impacted by joint degeneration …

Vibrational spectroscopy and imaging: applications for tissue engineering

W Querido, JM Falcon, S Kandel, N Pleshko - Analyst, 2017 - pubs.rsc.org
Tissue engineering (TE) approaches strive to regenerate or replace an organ or tissue. The
successful development and subsequent integration of a TE construct is contingent on a …

Incorporation of Rician noise in the analysis of biexponential transverse relaxation in cartilage using a multiple gradient echo sequence at 3 and 7 Tesla

M Bouhrara, DA Reiter, H Celik… - Magnetic resonance …, 2015 - Wiley Online Library
Purpose Previous work has evaluated the quality of different analytic methods for extracting
relaxation times from magnitude imaging data exhibiting Rician noise. However …

Anomalous T2 relaxation in normal and degraded cartilage

DA Reiter, RL Magin, W Li, JJ Trujillo… - Magnetic resonance …, 2016 - Wiley Online Library
Purpose To compare the ordinary monoexponential model with three anomalous relaxation
models—the stretched Mittag‐Leffler, stretched exponential, and biexponential functions …