Nitro-containing compounds are important structural moieties in drugs, natural products, and
small molecule therapeutics, and are widely used in a variety of organic transformations …

Nitroaromatic compounds play an important role in organic synthesis, medicinal chemistry
and chemical industry. Among the recently reported synthetic methods to access …

Synthetic transformations of otherwise inert C–H bonds have emerged as a powerful tool for
molecular modifications during the last decades, with broad applications towards …

The direct decarboxylative meta-selective C–H acylation of a wide range of arenes is
established via the ruthenium-catalyzed ortho-metalation strategy. This procedure, using …

In the past few decades, synthetic organic chemistry has been invigorated with the
development of transition metal catalyzed directing group assisted regioselective C–H …

A rhodium-catalyzed electrochemical regioselective annulation of 6-phenylpurines and 6-
phenyl-7-deazapurines with alkynes has been developed. Electricity is used to recycle the …

We have successfully modified a series of pyrrolo [2, 1-a] isoquinolines via direct nitration
under mild reaction conditions. Easily accessible nitrates including CAN, Cu (NO3) 2· H2O …

The gem-difluoroallyl group is a sought-after structural motif commonly found in
pharmaceutical compounds. Despite its appeal, achieving a controlled synthesis of both α, α …

With pyrimidine as the directing group, we achieved the meta-selective difluoromethylation
of phenol derivatives using ruthenium as a catalyst. This synthetic scheme provided an …

A practical meta C–H chlorination protocol is established via a Ru (0)-catalyzed ortho-
metalation strategy. The use of N-chloro-2, 10-camphorsultam as a new chlorinating agent is …