Cancer drug resistance: A brief overview from a genetic viewpoint
J Rueff, AS Rodrigues - Cancer Drug Resistance: Overviews and Methods, 2016 - Springer
Cancer drug resistance leading to therapeutic failure in the treatment of many cancers
encompasses various mechanisms and may be intrinsic relying on the patient's genetic …
encompasses various mechanisms and may be intrinsic relying on the patient's genetic …
MUTYH-associated tumor syndrome: The other face of MAP
L Magrin, D Fanale, C Brando, LR Corsini, U Randazzo… - Oncogene, 2022 - nature.com
MUTYH gene is involved in the base excision repair (BER) mechanism and its pathogenic
alterations are associated with colorectal polyposis and cancer. MUTYH-associated …
alterations are associated with colorectal polyposis and cancer. MUTYH-associated …
Overview of biological mechanisms of human carcinogens
N Birkett, M Al-Zoughool, M Bird, RA Baan… - Journal of Toxicology …, 2019 - Taylor & Francis
This review summarizes the carcinogenic mechanisms for 109 Group 1 human carcinogens
identified as causes of human cancer through Volume 106 of the IARC Monographs. The …
identified as causes of human cancer through Volume 106 of the IARC Monographs. The …
Search for new genetic biomarkers in poorly differentiated and anaplastic thyroid carcinomas using next generation sequencing
V Sykorova, S Dvorakova, J Vcelak… - Anticancer …, 2015 - ar.iiarjournals.org
Background: Poorly differentiated thyroid carcinoma (PDTC) and anaplastic thyroid
carcinoma (ATC) are very rare tumors with extremely aggressive behavior. Their …
carcinoma (ATC) are very rare tumors with extremely aggressive behavior. Their …
Downregulated LRRK2 gene expression inhibits proliferation and migration while promoting the apoptosis of thyroid cancer cells by inhibiting activation of the JNK …
ZC Jiang, XJ Chen, Q Zhou… - International …, 2019 - spandidos-publications.com
Emerging studies have indicated that leucine-rich repeat kinase 2 (LRRK2) is associated
with thyroid cancer (TC). The present study investigated the effect of LRRK2 on the cell cycle …
with thyroid cancer (TC). The present study investigated the effect of LRRK2 on the cell cycle …
Association Studies Between XRCC1, XRCC2, XRCC3 Polymorphisms and Differentiated Thyroid Carcinoma
L Yan, Q Li, X Li, H Ji, L Zhang - Cellular Physiology and Biochemistry, 2016 - karger.com
Abstract Background/Aims: DNA HRR pathway and BER pathway play vital roles in
differentiated thyroid cancer (DTC) development, thus we supposed that polymorphisms of …
differentiated thyroid cancer (DTC) development, thus we supposed that polymorphisms of …
OGG1 Mutations and Risk of Female Breast Cancer: Meta‐Analysis and Experimental Data
In first part of this study association between OGG1 polymorphisms and breast cancer
susceptibility was explored by meta‐analysis. Second part of the study involved 925 …
susceptibility was explored by meta‐analysis. Second part of the study involved 925 …
Polymorphisms of DNA Repair Genes in Thyroid Cancer
A Gielecińska, M Kciuk, D Kołat… - International Journal of …, 2024 - mdpi.com
The incidence of thyroid cancer, one of the most common forms of endocrine cancer, is
increasing rapidly worldwide in developed and developing countries. Various risk factors …
increasing rapidly worldwide in developed and developing countries. Various risk factors …
[HTML][HTML] Mismatch repair single nucleotide polymorphisms and thyroid cancer susceptibility
Thyroid cancer (TC) is the most common endocrine malignancy and its incidence continues
to rise worldwide. Ionizing radiation exposure is the best established etiological factor …
to rise worldwide. Ionizing radiation exposure is the best established etiological factor …
Polymorphisms of base-excision repair genes and the hepatocarcinogenesis
Aim To determine the possible association between polymorphisms of DNA repair genes,
including XRCC1 Arg194Tryp, Arg280His, and Arg399Glu, APE1 Asp148Glu, and NEIL2 …
including XRCC1 Arg194Tryp, Arg280His, and Arg399Glu, APE1 Asp148Glu, and NEIL2 …