Synthesis, antimicrobial, anticancer, PASS, molecular docking, molecular dynamic simulations & pharmacokinetic predictions of some methyl β-D-galactopyranoside …
A series of methyl β-D-galactopyranoside (MGP, 1) analogs were selectively acylated with
cinnamoyl chloride in anhydrous N, N-dimethylformamide/triethylamine to yield 6-O …
cinnamoyl chloride in anhydrous N, N-dimethylformamide/triethylamine to yield 6-O …
Methyl β-D-galactopyranoside esters as potential inhibitors for SARS-CoV-2 protease enzyme: synthesis, antimicrobial, PASS, molecular docking, molecular dynamics …
Carbohydrate esters are significant in medicinal chemistry because of their efficacy for the
synthesis of biologically active drugs. In the present study, methyl β-D-galactopyranoside …
synthesis of biologically active drugs. In the present study, methyl β-D-galactopyranoside …
[PDF][PDF] Monosaccharide derivatives: synthesis, antimicrobial, pass, antiviral and molecular docking studies against SARS-COV-2 Mpro inhibitors
F Yasmin, MR Amin, MA Hosen… - Cellul Chem …, 2021 - r.bangladeshhealthwatch.org
Several carbohydrate-based drugs are currently being used to treat a number of diseases in
humans worldwide. Thus, our research group has focused on the synthesis of new methyl α …
humans worldwide. Thus, our research group has focused on the synthesis of new methyl α …
[HTML][HTML] Computational investigation of methyl α-D-glucopyranoside derivatives as inhibitor against bacteria, fungi and COVID-19 (SARS-2)
For employing computational tools for drug discovery in the area of medicinal chemistry by
carbohydrates, methyl α-D-glucopyranoside and its ten acylated derivatives have picked up …
carbohydrates, methyl α-D-glucopyranoside and its ten acylated derivatives have picked up …
A computational investigation of galactopyranoside esters as antimicrobial agents through antiviral, molecular docking, molecular dynamics, pharmacokinetics, and …
One of the most common viral infections worldwide is the Human Papilloma Virus (HPV)
which has been linked to cancer and other diseases in many countries. Monosaccharide …
which has been linked to cancer and other diseases in many countries. Monosaccharide …
In silico and POM analysis for potential antimicrobial agents of thymidine analogs by using molecular docking, molecular dynamics and ADMET profiling
Nucleoside analogs are an important, well-established class of clinically useful medicinal
agents that exhibit potent antimicrobial activity. Thus, we designed to explore the synthesis …
agents that exhibit potent antimicrobial activity. Thus, we designed to explore the synthesis …
Novel Methyl 4, 6-O-Benzylidene--D-Glucopyranoside Derivatives: Synthesis, Structural Characterization and Evaluation of Antibacterial Activities
M Islam, A Arifuzzaman, M Rahman… - Hacettepe Journal of …, 2019 - dergipark.org.tr
Carbohydrates are the most abundant and the most diverse biopolymers in nature. Due to
the importance of carbohydrates it is necessary to develop a new method for the synthesis of …
the importance of carbohydrates it is necessary to develop a new method for the synthesis of …
[PDF][PDF] Microbial efficacy and two step synthesis of uridine derivatives with spectral characterization
SR Devi, S Jesmin, M Rahman… - ACTA …, 2019 - actapharmsci.com
Uridine is a natural nucleoside precursor of uridine monophosphate in organisms and thus
is considered to be safe and is used in a wide range of clinical settings. The farreaching …
is considered to be safe and is used in a wide range of clinical settings. The farreaching …
Design, synthesis, in silico and POM studies for the identification of the pharmacophore sites of benzylidene derivatives
Due to the uneven distribution of glycosidase enzyme expression across bacteria and fungi,
glycoside derivatives of antimicrobial compounds provide prospective and promising …
glycoside derivatives of antimicrobial compounds provide prospective and promising …
Chemically modified uridine molecules incorporating acyl residues to enhance antibacterial and cytotoxic activities
A new N-acetylsulfanilylation series of uridine have been synthesized in good yield using
direct acylation method and afforded the 5'-ON-acetylsulfanilyluridine. In order to obtain …
direct acylation method and afforded the 5'-ON-acetylsulfanilyluridine. In order to obtain …