Cyclodextrins (CD) and derivatives are functional excipients that can improve the
bioavailability of numerous drugs. Because of their drug solubility improving properties they …

The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

Transfection is a powerful analytical tool enabling studies of gene products and functions in
eukaryotic cells. Successful delivery of genetic material into cells depends on DNA quantity …

Recent advances in controlled/living polymerization techniques and highly efficient coupling
chemistries have enabled the facile synthesis of complex polymer architectures with …

The discovery of the first “living” radical polymerization by Otsu and co-workers (1) in 1982
heralded the start of a very exciting time for polymer chemists. Since then, a plethora of living …

Over the past decade, star polymers have been widely used in biomedical applications such
as drug delivery, gene delivery, tissue engineering, diagnosis, medical devices, and …

Gene-based therapies have emerged as a new modality for combating a myriad of currently
incurable diseases. However, the fragile nature of gene therapeutics has significantly …

Cyclodextrins (CDs) are a family of cyclic oligosaccharides with a hydrophilic exterior
surface and a nonpolar cavity interior, therefore, CDs can form inclusion complexes through …

Combination therapy through simultaneous delivery of anti-cancer drugs and genes with
nano-assembled structure has been proved to be a simple and effective approach for …

Conspectus Because of their biocompatibility, biodegradability, and unique bioactive
properties, polysaccharides have been recognized and directly applied as excellent …