Zwitterionic biomaterials

Q Li, C Wen, J Yang, X Zhou, Y Zhu, J Zheng… - Chemical …, 2022 - ACS Publications
The term “zwitterionic polymers” refers to polymers that bear a pair of oppositely charged
groups in their repeating units. When these oppositely charged groups are equally …

Synthetic alternatives to Matrigel

EA Aisenbrey, WL Murphy - Nature Reviews Materials, 2020 - nature.com
Matrigel, a basement-membrane matrix extracted from Engelbreth–Holm–Swarm mouse
sarcomas, has been used for more than four decades for a myriad of cell-culture …

Scaffolding biomaterials for 3D cultivated meat: prospects and challenges

C Bomkamp, SC Skaalure, GF Fernando… - Advanced …, 2022 - Wiley Online Library
Cultivating meat from stem cells rather than by raising animals is a promising solution to
concerns about the negative externalities of meat production. For cultivated meat to fully …

Advances in pluripotent stem cells: history, mechanisms, technologies, and applications

G Liu, BT David, M Trawczynski, RG Fessler - Stem cell reviews and …, 2020 - Springer
Over the past 20 years, and particularly in the last decade, significant developmental
milestones have driven basic, translational, and clinical advances in the field of stem cell …

Controlled modelling of human epiblast and amnion development using stem cells

Y Zheng, X Xue, Y Shao, S Wang, SN Esfahani, Z Li… - Nature, 2019 - nature.com
Early human embryonic development involves extensive lineage diversification, cell-fate
specification and tissue patterning. Despite its basic and clinical importance, early human …

Bioengineering strategies to accelerate stem cell therapeutics

CM Madl, SC Heilshorn, HM Blau - Nature, 2018 - nature.com
Although only a few stem cell-based therapies are currently available to patients, stem cells
hold tremendous regenerative potential, and several exciting clinical applications are on the …

Surface-initiated polymer brushes in the biomedical field: applications in membrane science, biosensing, cell culture, regenerative medicine and antibacterial coatings

M Krishnamoorthy, S Hakobyan, M Ramstedt… - Chemical …, 2014 - ACS Publications
Understanding and controlling interfaces has proven to be key to a very wide range of
applications, from optical and electronic materials 1, 2 to energy storage and production, 3 …

Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: a methods overview

CL Mummery, J Zhang, ES Ng, DA Elliott… - Circulation …, 2012 - Am Heart Assoc
Since human embryonic stem cells were first differentiated to beating cardiomyocytes a
decade ago, interest in their potential applications has increased exponentially. This has …

Human pluripotent stem cell culture: considerations for maintenance, expansion, and therapeutics

KG Chen, BS Mallon, RDG McKay, PG Robey - Cell stem cell, 2014 - cell.com
Human pluripotent stem cells (hPSCs) provide powerful resources for application in
regenerative medicine and pharmaceutical development. In the past decade, various …

Extracellular matrix promotes highly efficient cardiac differentiation of human pluripotent stem cells: the matrix sandwich method

J Zhang, M Klos, GF Wilson, AM Herman… - Circulation …, 2012 - Am Heart Assoc
Rationale: Cardiomyocytes (CMs) differentiated from human pluripotent stem cells (PSCs)
are increasingly being used for cardiovascular research, including disease modeling, and …