Enhancing clinical potential of liquid biopsy through a multi-omic approach: A systematic review

G Di Sario, V Rossella, ES Famulari, A Maurizio… - Frontiers in …, 2023 - frontiersin.org
In the last years, liquid biopsy gained increasing clinical relevance for detecting and
monitoring several cancer types, being minimally invasive, highly informative and replicable …

Insights into circulating tumor cell clusters: A barometer for treatment effects and prognosis for prostate cancer patients

L Lu, W Hu, B Liu, T Yang - Cancers, 2022 - mdpi.com
Simple Summary Circulating tumor cells (CTCs) are a promising biomarker for the risk of
prostate cancer aggressiveness and metastasis and play a role in the processes of tumor …

[HTML][HTML] Exchange of cellular components between platelets and tumor cells: impact on tumor cells behavior

A Rodriguez-Martinez, I Simon-Saez, S Perales… - Theranostics, 2022 - ncbi.nlm.nih.gov
Background: Platelets are active players in tumorigenesis, although the exact interactive
mechanisms and their direct impact on tumor cells remain largely unknown. Methods …

Circulating tumor cell clusters are cloaked with platelets and correlate with poor prognosis in unresectable pancreatic cancer

M Lim, S Park, HO Jeong, SH Park, S Kumar, A Jang… - Cancers, 2021 - mdpi.com
Simple Summary Despite recent advances, some patients with pancreatic cancer are
refractory to treatment and the disease rapidly progresses, resulting in early death. The …

Platelet-coated circulating tumor cells are a predictive biomarker in patients with metastatic castrate-resistant prostate cancer

S Chai, N Matsumoto, R Storgard, CC Peng… - Molecular Cancer …, 2021 - AACR
Metastatic castration-resistant prostate cancer (mCRPC) includes a subset of patients with
particularly unfavorable prognosis characterized by combined defects in at least two of three …

Recent advances in blood-based liquid biopsy approaches in prostate cancer

AK Cani, SS Salami - The Cancer Journal, 2023 - journals.lww.com
The advent of high-throughput technologies has enabled the analysis of minute amounts of
tumor-derived material purified from body fluids, termed “liquid biopsies.” Prostate cancer …

Circulating tumour cell numbers correlate with platelet count and circulating lymphocyte subsets in men with advanced prostate cancer: Data from the ExPeCT clinical …

B Hayes, L Brady, G Sheill, AM Baird, E Guinan… - Cancers, 2021 - mdpi.com
Simple Summary Cancer cells (CTCs) can be found in the bloodstream in men with
advanced prostate cancer. Blood platelets, which normally help the blood to clot, may help …

Circulating Tumor Cells: How Far Have We Come with Mining These Seeds of Metastasis?

V Radhakrishnan, JT Kaifi, KN Suvilesh - Cancers, 2024 - mdpi.com
Simple Summary Circulating tumor cells are cancer cells that detach from the primary tumor
and enter the bloodstream. These cancer cells in the blood stream eventually result in …

A Holistic Approach to Hard-to-Treat Cancers: The Future of Immunotherapy for Glioblastoma, Triple Negative Breast Cancer, and Advanced Prostate Cancer

C Puig-Saenz, JRD Pearson, JE Thomas, SEB McArdle - Biomedicines, 2023 - mdpi.com
Immunotherapy represents an attractive avenue for cancer therapy due to its tumour
specificity and relatively low frequency of adverse effects compared to other treatment …

ExPeCT: a randomised trial examining the impact of exercise on quality of life in men with metastatic prostate cancer

G Sheill, L Brady, B Hayes, AM Baird, E Guinan… - Supportive Care in …, 2023 - Springer
Purpose All patients living with cancer, including those with metastatic cancer, are
encouraged to be physically active. This paper examines the secondary endpoints of an …