Metabolic alterations are a key hallmark of cancer cells, and the augmented synthesis and
use of nucleotide triphosphates is a critical and universal metabolic dependency of cancer …

This review aims to serve as an introduction to the solute carrier proteins (SLC) superfamily
of transporter proteins and their roles in human cells. The SLC superfamily currently …

T cells play a critical role in cancer control, but a range of potent immunosuppressive
mechanisms can be upregulated in the tumor microenvironment (TME) to abrogate their …

The microbes and microbial pathways that influence host inflammatory disease progression
remain largely undefined. Here, we show that variation in atherosclerosis burden is partially …

Neuronal activity creates an intense energy demand that must be met by rapid metabolic
responses. To investigate metabolic adaptations in the neuron-enriched dentate granule cell …

Background Lactobacillus species in gut microbiota shows great promise in alleviation of
metabolic diseases. However, little is known about the molecular mechanism of how …

Abstract ENPP1 (ecto-nucleotide pyrophosphatase/phosphodiesterase) participates in the
hydrolysis of different purine nucleotides in an array of physiologic processes. However …

Nicotinamide riboside (NR) is a form of vitamin B 3 and is one of the most studied
compounds for the restoration of cellular NAD+ levels demonstrating clinical potential in …

In modern societies, with an increase in the older population, age-related
neurodegenerative diseases have progressively become greater socioeconomic burdens …

Pulmonary fibrosis is a debilitating and life-limiting lung condition in which the damage-
response mechanisms of mixed-population cells within the lungs go awry. The tissue …