Exercise-induced oxidative stress: cellular mechanisms and impact on muscle force production
SK Powers, MJ Jackson - Physiological reviews, 2008 - journals.physiology.org
The first suggestion that physical exercise results in free radical-mediated damage to tissues
appeared in 1978, and the past three decades have resulted in a large growth of knowledge …
appeared in 1978, and the past three decades have resulted in a large growth of knowledge …
[HTML][HTML] Reactive oxygen species: impact on skeletal muscle
It is well established that contracting muscles produce both reactive oxygen and nitrogen
species. Although the sources of oxidant production during exercise continue to be debated …
species. Although the sources of oxidant production during exercise continue to be debated …
Diet, obesity, and depression: a systematic review
Background: Obesity and depression co-occur in a significant proportion of the population.
Mechanisms linking the two disorders include the immune and the endocrine system …
Mechanisms linking the two disorders include the immune and the endocrine system …
Development and evaluation of AS03, an Adjuvant System containing α-tocopherol and squalene in an oil-in-water emulsion
N Garçon, DW Vaughn… - Expert review of …, 2012 - Taylor & Francis
AS03 is an Adjuvant System composed of α-tocopherol, squalene and polysorbate 80 in an
oil-in-water emulsion. In various nonclinical and clinical studies, high levels of antigen …
oil-in-water emulsion. In various nonclinical and clinical studies, high levels of antigen …
Molecular mechanism of α-tocopherol action
A Azzi - Free Radical Biology and Medicine, 2007 - Elsevier
The inability of other antioxidants to substitute for α-tocopherol in a number of cellular
reactions, the lack of a compensatory antioxidant response in the gene expression under …
reactions, the lack of a compensatory antioxidant response in the gene expression under …
Vitamin E in human health and disease
Vitamin E in nature is comprised of a family of tocopherols and tocotrienols. The most
studied of these is α-tocopherol (α-TOH), because this form is retained within the body, and …
studied of these is α-tocopherol (α-TOH), because this form is retained within the body, and …
Muscle redox signalling pathways in exercise. Role of antioxidants
SA Mason, D Morrison, GK McConell… - Free Radical Biology and …, 2016 - Elsevier
Recent research highlights the importance of redox signalling pathway activation by
contraction-induced reactive oxygen species (ROS) and nitric oxide (NO) in normal exercise …
contraction-induced reactive oxygen species (ROS) and nitric oxide (NO) in normal exercise …
Influence of vitamin C and vitamin E on redox signaling: Implications for exercise adaptations
The exogenous antioxidants vitamin C (ascorbate) and vitamin E (α-tocopherol) often blunt
favorable cell signaling responses to exercise, suggesting that redox signaling contributes to …
favorable cell signaling responses to exercise, suggesting that redox signaling contributes to …
Relationship between serum alpha-tocopherol and overall and cause-specific mortality: a 30-year prospective cohort analysis
Rationale: Although there has been a long-standing interest in the human health effects of
vitamin E, a comprehensive analysis of the association between circulating vitamin E and …
vitamin E, a comprehensive analysis of the association between circulating vitamin E and …
[HTML][HTML] Higher baseline serum concentrations of vitamin E are associated with lower total and cause-specific mortality in the Alpha-Tocopherol, Beta-Carotene …
ME Wright, KA Lawson, SJ Weinstein, P Pietinen… - The American journal of …, 2006 - Elsevier
Background: A meta-analysis of 19 trials suggested a small increase in the risk of all-cause
mortality with high-dose vitamin E supplementation. Little is known, however, about the …
mortality with high-dose vitamin E supplementation. Little is known, however, about the …