Advances in experimental models of rheumatoid arthritis

S Wang, Y Zhou, J Huang, H Li, H Pang… - European journal of …, 2023 - Wiley Online Library
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by
persistent articular inflammation and joint damage. RA was first described over 200 years …

[PDF][PDF] Pathogenesis of Collagen-Induced Arthritis: Role of Immune Cells with Associated Cytokines and Antibodies, Comparison with Rheumatoid Arthritis.

M Šteigerová, M Šíma, O Slanař - Folia Biologica (00155500), 2023 - researchgate.net
Collagen-induced arthritis is the most common in vivo model of rheumatoid arthritis used for
investigation of new potential therapies in preclinical research. Rheumatoid arthritis is a …

Development of tri‐layered biomimetic atelocollagen scaffolds with interfaces for osteochondral tissue engineering

R Cao, Y Xu, Y Xu, DD Brand, G Zhou… - Advanced …, 2022 - Wiley Online Library
The development of biomimetic scaffolds containing cartilage, calcified cartilage, and bone
regeneration for precise osteochondral repair remains a challenge. Herein, a novel tri …

[HTML][HTML] A synergistic effect of triptolide and curcumin on rheumatoid arthritis by improving cell proliferation and inducing cell apoptosis via inhibition of the IL-17/NF-κB …

C Zhang, Y Weng, H Wang, S Zhan, C Li… - International …, 2024 - Elsevier
Rheumatoid arthritis (RA) is a chronic, progressive, systemic autoimmune disease. While
triptolide (TPL) and curcumin (CUR) are known to have multiple beneficial effects on RA, the …

Combination of inorganic nitrate and vitamin C prevents collagen-induced arthritis in rats by inhibiting pyroptosis

H Zhang, Y Zhang, Y Zhang, H Wei, S Jin, T Huo… - Food & Function, 2025 - pubs.rsc.org
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease characterized by
synovial inflammation, cartilage damage, and bone loss. Although effective treatments are …

Fu-zi decoction attenuate rheumatoid arthritis in vivo and in vitro by modulating RANK/RANKL signaling pathway

Z Pan, F Li, Y Xu, H Ye, J Liu, Z Wang… - Frontiers in …, 2024 - frontiersin.org
Background Fu-zi decoction (FZD) has a long history of application for treating Rheumatoid
arthritis (RA) as a classic formulation. However, its underlying mechanisms have not been …

Analysis of Chemical Constituents of Miao Ethnomedicine Heiguteng Zhuifeng Huoluo Capsule (HZFC) and the Discovery of Active Substances in the Treatment of …

K Mu, L Li, Y Chen, M Zhang, T He, K Li, Y Liu… - ACS omega, 2024 - ACS Publications
In this study, the chemical substances of Heiguteng Zhuifeng Huoluo Capsule (HZFC) and
its potential active ingredients for the treatment of rheumatoid arthritis (RA) were …

[HTML][HTML] Animal Models: Catalysts for Advancing Topical Treatments in Rheumatoid Arthritis

M Kumari, D Gohil, P Sadhu, C Talele… - Journal of Young …, 2024 - jyoungpharm.org
Rheumatoid Arthritis (RA) is a chronic autoimmune condition causing joint inflammation and
damage. Despite treatment progress, effective topical therapies pose challenges. Animal …

黑龙骨茎叶抗类风湿性关节炎作用研究

刘刚, 王瑞鑫, 刘育辰, 穆开朗, 安兰兰, 周环娟 - 中国药事, 2024 - zgys.nifdc.org.cn
目的: 研究苗药黑龙骨茎叶对胶原诱导性关节炎(Collagen-induced Arthritis, CIA)
模型大鼠类风湿性关节炎(Rheumatoid Arthritis, RA) 作用, 探究黑龙骨茎叶抗RA …

链脲佐菌素诱导的糖尿病模型小鼠对炎症性关节炎的影响

刘莉玄, 李莉, 陈昱颖, 胡星云, 宋卫东… - 岭南现代临床外科, 2021 - lingnanwaike.com
目的探讨链脲佐菌素(STZ) 诱导的Ⅰ 型糖尿病模型对小鼠炎症性关节炎的影响. 方法将16 只6
周龄SPF 级雄性C57BL/6J 小鼠随机分成两组, 每组8 只. 糖尿病组小鼠采用于6 …