Artificial biocatalytic linear cascades for preparation of organic molecules

JH Schrittwieser, S Velikogne, M Hall… - Chemical …, 2018 - ACS Publications
The review compiles artificial cascades involving enzymes with a focus on the last 10 years.
A cascade is defined as the combination of at least two reaction steps in a single reaction …

Enzymatic reductions for the chemist

F Hollmann, IWCE Arends, D Holtmann - Green Chemistry, 2011 - pubs.rsc.org
When challenged by a difficult reduction reaction, a chemist should always also consider
biocatalysis in synthesis planning. The inherent selectivity of enzymes has been known for …

Enantioselective enzymatic desymmetrizations in organic synthesis

E García-Urdiales, I Alfonso, V Gotor - Chemical Reviews, 2005 - ACS Publications
During the recent past years, tremendous efforts have been made to establish
enantioselective routes for the preparation of enantiomerically pure compounds due to their …

Recent advances in biotechnological applications of alcohol dehydrogenases

YG Zheng, HH Yin, DF Yu, X Chen, XL Tang… - Applied microbiology …, 2017 - Springer
Alcohol dehydrogenases (ADHs), which belong to the oxidoreductase superfamily, catalyze
the interconversion between alcohols and aldehydes or ketones with high stereoselectivity …

[PDF][PDF] How Green is Biocatalysis? To Calculate is To Know.

Y Ni, D Holtmann, F Hollmann - ChemCatChem, 2014 - researchgate.net
Green chemistry aims to minimize the environmental hazards of chemical processes and
their products. Ever since its introduction by Anastas,[1] this principle has inspired …

Asymmetric H2O-Nucleophilic Ring Opening of D–A Cyclopropanes: Catalyst Serves as a Source of Water

QK Kang, L Wang, QJ Liu, JF Li… - Journal of the American …, 2015 - ACS Publications
The first catalytic enantioselective ring-opening reaction of donor–acceptor cyclopropanes
with water is described. By employing Cy-TOX/Cu (II) as catalyst, the reaction performed …

Use of a Robust Dehydrogenase from an Archael Hyperthermophile in Asymmetric Catalysis−Dynamic Reductive Kinetic Resolution Entry into (S)-Profens

JA Friest, Y Maezato, S Broussy, P Blum… - Journal of the …, 2010 - ACS Publications
Described is an efficient heterologous expression system for Sulfolobus solfataricus ADH-10
(Alcohol Dehydrogenase isozyme 10) and its use in the dynamic reductive kinetic resolution …

Exploiting enzymatic dynamic reductive kinetic resolution (DYRKR) in stereocontrolled synthesis

GA Applegate, DB Berkowitz - Advanced synthesis & catalysis, 2015 - Wiley Online Library
Over the past two decades, the domains of both frontline synthetic organic chemistry and
process chemistry have seen an increase in crosstalk between asymmetric organic …

A photocatalyst/enzyme couple that uses solar energy in the asymmetric reduction of acetophenones

S Choudhury, JO Baeg, NJ Park, RK Yadav - Angewandte Chemie, 2012 - infona.pl
Sonnenanbeter: Ein gekoppeltes Photokatalysator‐Enzym‐System als neuartiges
künstliches Photosynthesesystem sammelt Solarenergie nach dem Vorbild von …

Asymmetric chemoenzymatic synthesis of miconazole and econazole enantiomers. The importance of chirality in their biological evaluation

J Mangas-Sánchez, E Busto… - The Journal of …, 2011 - ACS Publications
A simple and novel chemoenzymatic route has been applied for the first time in the synthesis
of miconazole and econazole single enantiomers. Lipases and oxidoreductases have been …