Discovery of plant-derived anti-tumor natural products: Potential leads for anti-tumor drug discovery

Z Hui, H Wen, J Zhu, H Deng, X Jiang, XY Ye… - Bioorganic …, 2024 - Elsevier
Natural products represent a paramount source of novel drugs. Numerous plant-derived
natural products have demonstrated potent anti-tumor properties, thereby garnering …

Promises of phytochemical based nano drug delivery systems in the management of cancer

P Kumar, N Yadav, B Chaudhary, V Jain… - Chemico-Biological …, 2022 - Elsevier
Cancer is the leading cause of human disease and death worldwide, accounting for 7.6
million deaths per year and projected to reach 13.1 million by 2030. Many phytochemicals …

1, 4‐Naphthoquinone Analogs and Their Application as Antibacterial Agents

W Wang, CWT Chang, Q Zhang - ChemistrySelect, 2022 - Wiley Online Library
Antimicrobial resistance threatens the effective prevention and treatment of an ever‐
increasing range of infections caused by different types of bacteria. Addressing antibacterial …

The Effectiveness of Isoplumbagin and Plumbagin in Regulating Amplitude, Gating Kinetics, and Voltage-Dependent Hysteresis of erg-mediated K+ Currents

L Chen, HY Cho, TH Chuang, TL Ke, SN Wu - Biomedicines, 2022 - mdpi.com
Isoplumbagin (isoPLB, 5-hydroxy-3-methyl-1, 4-naphthoquinone), a naturally occurring
quinone, has been observed to exercise anti-inflammatory, antimicrobial, and antineoplastic …

In vitro efficacy of plumbagin and thymol against Theileria annulata

EE Titus, A Palavesam, SM Rajaram, P Perumal… - Journal of Parasitic …, 2023 - Springer
Phytochemical compounds, plumbagin and thymol were evaluated for their efficacy against
Theileria annulata using MTT cell viability assay. Plumbagin and thymol were found to be …

Establishment of a jaw fibrosarcoma patient-derived xenograft and evaluation of the tumor suppression efficacy of plumbagin against jaw fibrosarcoma

Y Xin, S Li, Q Jiang, F Hu, Y He, J Zhang - Frontiers in oncology, 2020 - frontiersin.org
Background: Head and neck fibrosarcoma is a rare malignant tumor, accounting for about
1% of all head and neck tumors. It can also occur in the jaw bone, for which surgical …

Cytotoxic compounds from the stems of Diospyros ehretioides and their bioactivity

P Wosawat, T Senawong, N Suchaichit… - Natural Product …, 2021 - Taylor & Francis
A new (naphthalenyl) methyl acetate,(1, 4, 5-trimethoxynaphthalen-2-yl) methyl acetate (1)
and (±)-4, 5-dihydroxy-2-methyltetralone (2) were isolated together with five lupane …

Hemisynthesis of Pentacyclic Triterpenoids from Diospyros foxworthyi with In vitro and In silico Anti-malarial Evaluation

MS Abd Ghani, NAL Abu Bakar… - Current Organic …, 2024 - ingentaconnect.com
A total of twelve pentacyclic triterpenoid derivatives based on betulin (1) and lupeol (2)
scaffolds isolated from Diospyros foxworthyi were hemisynthesized by acylation or …

白花丹醌通过E-cadherin 增强替莫唑胺对人脑胶质瘤U251 细胞迁移和侵袭的抑制作用

蔡卫, 陈宏璘, 张建永, 杨远维, 王洁, 彭康 - 肿瘤防治研究, 2021 - zlfzyj.com
白花丹醌通过E-cadherin增强替莫唑胺对人脑胶质瘤U251细胞迁移和侵袭的抑制作用蔡卫,
陈宏璘, 张 Page 1 白花丹醌通过E-cadherin增强替莫唑胺对人脑胶质瘤U251细胞迁移和侵袭的 …

Antibacterial potential and drug discovery of genus Diospyros: A review

R Pandey, R Verma, KK Prajapati, VS Pandey… - 2024 - indianjournals.com
Many species of genus Diospyros have been tested and evaluated for their antibacterial
activities. Plant extracts, isolated phytoconstituents, essential oils as well as …