Toxic aggregated amyloid-β accumulation is a key pathogenic event in Alzheimer's disease.
Treatment approaches have focused on the suppression, deferral, or dispersion of amyloid …

Neurofibrillary tangles (NFT) is one of the hallmarks of Alzheimer's disease (AD). Recent
research suggests that pretangle tau, the soluble precursor of NFT, is an initiator for AD …

Aβ aggregation-related neuroinflammation and imbalance of brain glucose homeostasis
play important roles in the pathological process of Alzheimer's disease (AD). Chlorogenic …

Spatiotemporal control for supramolecular polymerization has rendered a paradigm shift
towards designing complex multi‐component supramolecular materials and derived …

Alzheimer's disease is a neurodegenerative pathology whose pathognomonic hallmarks are
increased generation of β-amyloid (Aβ) peptide, production of hyperphosphorylated (pTau) …

Introduction Ribonucleic acid (RNA) therapeutics are a new class of drugs whose
importance is highlighted by the growing number of molecules in the clinic. Sources of data …

Spinocerebellar ataxia (SCA) is an autosomal dominant neurodegenerative disease (ND)
with a high mortality rate. Symptomatic treatment is the only clinically adopted treatment …

Brain-targeted gene delivery across the blood-brain barrier (BBB) is a significant challenge
in the 21st century for the healthcare sector, particularly in developing an effective treatment …

The traits of Alzheimer's disease (AD) include amyloid plaques made of Aβ 1-40 and Aβ 1-
42, and neurofibrillary tangles by the hyperphosphorylation of tau protein. AD is a complex …

Abstract Glycogen synthase kinase‐3 (GSK3), consisting of GSK3α and GSK3β subtypes, is
a complex protein kinase that regulates numerous substrates. Research has observed …