Small animal PET: a review of what we have done and where we are going

RS Miyaoka, AL Lehnert - Physics in Medicine & Biology, 2020 - iopscience.iop.org
Small animal research is an essential tool in studying both pharmaceutical biodistribution
and disease progression over time. Furthermore, through the rapid development of in vivo …

Evolution of PET detectors and event positioning algorithms using monolithic scintillation crystals

A Gonzalez-Montoro, AJ Gonzalez… - … on Radiation and …, 2021 - ieeexplore.ieee.org
The use of monolithic scintillator-based photon detectors in positron emission tomography
(PET) has emerged as an attractive alternative to traditional pixelated array designs …

A neural network-based algorithm for simultaneous event positioning and timestamping in monolithic scintillators

P Carra, MG Bisogni, E Ciarrocchi… - Physics in Medicine …, 2022 - iopscience.iop.org
Objective. Monolithic scintillator crystals coupled to silicon photomultiplier (SiPM) arrays are
promising detectors for PET applications, offering spatial resolution around 1 mm and depth …

Enhancing the image quality via transferred deep residual learning of coarse PET sinograms

X Hong, Y Zan, F Weng, W Tao… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
Increasing the image quality of positron emission tomography (PET) is an essential topic in
the PET community. For instance, thin-pixelated crystals have been used to provide high …

Sub-millimetre DOI detector based on monolithic LYSO and digital SiPM for a dedicated small-animal PET system

R Marcinkowski, P Mollet, R Van Holen… - Physics in Medicine …, 2016 - iopscience.iop.org
The mouse model is widely used in a vast range of biomedical and preclinical studies.
Thanks to the ability to detect and quantify biological processes at the molecular level in …

A 32 mm× 32 mm× 22 mm monolithic LYSO: Ce detector with dual-sided digital photon counter readout for ultrahigh-performance TOF-PET and TOF-PET/MRI

G Borghi, BJ Peet, V Tabacchini… - Physics in Medicine & …, 2016 - iopscience.iop.org
New applications for positron emission tomography (PET) and combined PET/magnetic
resonance imaging (MRI) are currently emerging, for example in the fields of neurological …

Towards monolithic scintillator based TOF-PET systems: practical methods for detector calibration and operation

G Borghi, V Tabacchini… - Physics in Medicine & …, 2016 - iopscience.iop.org
Gamma-ray detectors based on thick monolithic scintillator crystals can achieve spatial
resolutions< 2 mm full-width-at-half-maximum (FWHM) and coincidence resolving times …

Recent developments in photodetection for medical applications

G Llosá - Nuclear Instruments and Methods in Physics Research …, 2015 - Elsevier
The use of the most advanced technology in medical imaging results in the development of
high performance detectors that can significantly improve the performance of the medical …

Experimental Validation of an Efficient Fan-Beam Calibration Procedure for -Nearest Neighbor Position Estimation in Monolithic Scintillator Detectors

G Borghi, V Tabacchini, S Seifert… - IEEE Transactions on …, 2015 - ieeexplore.ieee.org
Monolithic scintillator detectors can achieve excellent spatial resolution and coincidence
resolving time. However, their practical use for positron emission tomography (PET) and …

Localisation of gamma-ray interaction points in thick monolithic CeBr3 and LaBr3: Ce scintillators

A Ulyanov, O Morris, OJ Roberts, I Tobin… - Nuclear Instruments and …, 2017 - Elsevier
Localisation of gamma-ray interaction points in monolithic scintillator crystals can simplify
the design and improve the performance of a future Compton telescope for gamma-ray …