Since the concept and operational definition of “cognitive frailty”(simultaneous presence of
physical frailty and cognitive impairment without concurrent dementia) were proposed by the …

Cognitive frailty, defined as the coexistence of mild cognitive impairment symptoms and
physical frailty phenotype in older persons, is increasingly considered the main geriatric …

Abstract Background and Objectives Frailty describes an increased vulnerability to adverse
events such as disease or injury. Combating this state remains a major challenge for …

Background Physical frailty, characterized by reduced physiologic complexity and ability to
cope with stressors, is closely associated with cognitive impairment, which increases the risk …

BACKGROUND Physical frailty is a powerful tool for identifying nondisabled individuals at
high risk of adverse outcomes. The extent to which cognitive impairment in those without …

Abstract Background and Objectives This review aimed to summarize the association
between cognitive frailty (presence of frailty and cognitive impairment) and the risk of …

Our objectives were to evaluate: 1) the associations of cognitive frailty with various health
outcomes including disability, hospitalization, and death; 2) whether the associations …

Background: Cognitive aging is a dynamic process in late life with significant heterogeneity
across individuals. Objective: To review the evidence for latent classes of cognitive …

Background The association between frailty and adverse outcomes has been clearly
defined. Frailty is associated with age, but different frailty evolution patterns might determine …

Objective This systematic review and meta-analysis aimed to investigate the impact of
resistance training on brain-derived neurotrophic factor (BDNF) and depression among …