Powder transport systems are ubiquitous in various industries, where they can encounter
single powder flow, two-phase flow with solids carried by gas or liquid, and gas–solid–liquid …

The tablet manufacturing process is a complex system, especially in continuous
manufacturing (CM). It includes multiple unit operations, such as mixing, granulation, and …

Discrete element method (DEM) is an effective approach to investigate non-spherical
granular systems that are widely encountered in nature, industry, and our daily life. To …

In continuous manufacturing (CM) of pharmaceutical tablets, the residence time distribution
(RTD) of the tablet press feed frame plays an important role in ensuring the critical quality …

A recently proposed multi-level coarse-graining method (MCG) for DEM simulation [1] is
demonstrated in this work for two additional powder handling systems, namely, a hopper …

Powder flow in rotary tablet presses, constituting one of the key machines in the tablet
production chain, is today still considered as a black box. In this study, a discrete element …

The feed frame is a force-feeding device used in the die filling process. The die filling
process is crucial within pharmaceutical manufacturing to guarantee the critical quality …

The discrete element modelling (DEM) is the popular modelling technique devoted to the
modelling of discontinuous and granular materials. Calibration of DEM model parameters …

The aim of present study was to develop folate receptor targeted lipoprotein-mimetic
nanoparticles of resveratrol (RSV). Lipoprotein-mimicking nanocarrier (RSV-FA-LNPs) …

In the pharmaceutical industry, tablets are a common dosage form. As part of the
manufacturing process, powder in a tablet press passes through a feeding system called the …