Polycomb group genes (PcGs) are epigenetic effectors, essential for stem cell self-renewal
and pluripotency. Two main Polycomb repressive complexes (PRC1, PRC2) mediate gene …

Successful development and use of biomarkers will improve the productivity of oncology
drug development. Recognition of the importance of biomarkers for speeding drug …

The development of breast cancer is thought to occur through a multi-step process. The
majority of breast cancers likely develop over extended periods of time arising from early …

This paper presents a biological microelectromechanical system for injecting foreign
particles into thousands of cells simultaneously. The system inserts an array of microneedles …

Breast cancer prevention research has made remarkable progress in the past decade. Much
of this progress has come from clinical trials. However, in the future to test the many …

In October 2002, the AACR pioneered and hosted the first major annual meeting devoted to
cancer prevention. This signal event marked the rapid movement of cancer prevention to the …

Small-animal imaging with positron emission tomography (PET) has become a valuable tool
for evaluating preclinical models of breast cancer and other diseases. In this review, we …

Breast cancer is the most prevalent tumor in American woman. Multiple factors, including
age, diet, genetics, environment, geographic location, parity, as well as race, influence the …

Abstract The C3 (1) component of the rat prostate steroid binding protein has been used to
target expression of the SV40 T/t-antigen to the mammary epithelium of mice resulting in pre …

Numerous mouse models for mammary cancer have been developed and characterized
based upon their biological, molecular, and histopathological features. In an effort to dissect …