Abstract Familial Mediterranean fever (FMF)(OMIM# 249100) is the most common hereditary
autoinflammatory disease in the world. FMF is caused by gain of function mutations of MEFV …

The outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection has posed the world at a pandemic risk. Coronavirus-19 disease (COVID-19) is an …

Neutrophils are the most abundant innate immune cells in the circulation and they are the
first cells recruited to sites of infection or inflammation. Almost half of the intracellular protein …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Objectives The release of neutrophil extracellular traps (NETs) represents a novel neutrophil
effector function in systemic lupus erythematosus (SLE) pathogenesis. However, the …

Following strong activation signals, several types of immune cells reportedly release
chromatin and granular proteins into the extracellular space, forming DNA traps. This …

Acute pulmonary embolism generally resolves within 6 months. However, if the thrombus is
infected, venous thrombi transform into fibrotic vascular obstructions leading to chronic deep …

Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory
disease (AID) affecting mainly the ethnic groups originating from Mediterranean basin. The …

Neutrophils derive from hematopoietic stem cells (HSCs) with systemic inflammation driving
their activation and differentiation to myeloid progenitors to ensure enhanced myelopoiesis …

Almost all cell types release extracellular vesicles (EVs), which are derived either from
multivesicular bodies or from the plasma membrane. EVs contain a subset of proteins, lipids …