Circulating tumor DNA and minimal residual disease (MRD) in solid tumors: current horizons and future perspectives

Y Peng, W Mei, K Ma, C Zeng - Frontiers in oncology, 2021 - frontiersin.org
Circulating tumor DNA (ctDNA) is cell-free DNA (cfDNA) fragment in the bloodstream that
originates from malignant tumors or circulating tumor cells. Recently, ctDNA has emerged as …

ctDNA as a cancer biomarker: A broad overview

LS Pessoa, M Heringer, VP Ferrer - Critical reviews in oncology …, 2020 - Elsevier
Circulating tumor DNA (ctDNA) in fluids has gained attention because ctDNA seems to
identify tumor-specific abnormalities, which could be used for diagnosis, follow-up of …

The practicality of the use of liquid biopsy in early diagnosis and treatment monitoring of oral cancer in resource-limited settings

HA Adeola, IO Bello, RT Aruleba, NM Francisco… - Cancers, 2022 - mdpi.com
Simple Summary Mouth cancer often results in poor outcomes and requires the use of state-
of-the-art medical approaches to make its detection easy, individualized, and early. Liquid …

Circulating cell-free DNA or circulating tumor DNA in the management of ovarian and endometrial cancer

Q Chen, ZH Zhang, S Wang, JH Lang - OncoTargets and therapy, 2019 - Taylor & Francis
Ovarian cancer (OC) is the most lethal cancer of all gynecological malignancies, while
endometrial cancer (EC) is the most common one. Current strategies for OC/EC diagnosis …

Current status of ctDNA in precision oncology for hepatocellular carcinoma

Y Li, Y Zheng, L Wu, J Li, J Ji, Q Yu, W Dai… - Journal of Experimental …, 2021 - Springer
The conventional method used to obtain a tumor biopsy for hepatocellular carcinoma (HCC)
is invasive and does not evaluate dynamic cancer progression or assess tumor …

Quantitative analysis and monitoring of EZH2 mutations using liquid biopsy in follicular lymphoma

Á Nagy, B Bátai, A Balogh, S Illés, G Mikala, N Nagy… - Genes, 2020 - mdpi.com
Recent advances in molecular technologies enable sensitive and quantitative assessment
of circulating tumor DNA, offering a noninvasive disease monitoring tool for patients with …

Minimal residual disease (MRD) detection in solid tumors using circulating tumor DNA: a systematic review

L Zhu, R Xu, L Yang, W Shi, Y Zhang, J Liu, X Li… - Frontiers in …, 2023 - frontiersin.org
Minimal residual disease (MRD) refers to a very small number of residual tumor cells in the
body during or after treatment, representing the persistence of the tumor and the possibility …

Liquid biopsy with cell free DNA: new horizons for prostate cancer

G Ponti, M Maccaferri, A Percesepe… - Critical reviews in …, 2021 - Taylor & Francis
Although prostate cancer (PCa) is one of the most common tumors in European males, the
only minimally invasive diagnostic tool in PCa setup is the determination of PSA in serum …

The minimal residual disease using liquid biopsies in hematological malignancies

R Colmenares, N Álvarez, S Barrio, J Martínez-López… - Cancers, 2022 - mdpi.com
Simple Summary Monitoring the response to treatment in hematologic malignancies is
essential in defining the best way to optimize patient management. In general, achieving a …

Fe Single-Atom Carbon Dots Nanozyme Collaborated with Nucleic Acid Exonuclease III-Driven DNA Walker Cascade Amplification Strategy for Circulating Tumor …

Y Long, J Zhao, W Ma, C He, W Pei, J Hou… - Analytical …, 2024 - ACS Publications
Circulating tumor DNA (ctDNA), as a next-generation tumor marker, enables early screening
and monitoring of cancer through noninvasive testing. Exploring the development of new …