Pemphigus: current and future therapeutic strategies

D Didona, R Maglie, R Eming, M Hertl - Frontiers in immunology, 2019 - frontiersin.org
Pemphigus encompasses a heterogeneous group of autoimmune blistering diseases, which
affect both mucous membranes and the skin. The disease usually runs a chronic-relapsing …

Rituximab in multiple sclerosis: are we ready for regulatory approval?

S Brancati, L Gozzo, L Longo, DC Vitale… - Frontiers in …, 2021 - frontiersin.org
Despite the availability of a lot of effective disease-modifying drugs, multiple sclerosis
(MS)(in particular the progressive forms) still represents an important unmet medical need …

A British Society for Haematology Guideline: diagnosis and management of thrombotic thrombocytopenic purpura and thrombotic microangiopathies

M Scully, R Rayment, A Clark… - British journal of …, 2023 - Wiley Online Library
The objective of this guideline is to provide healthcare professionals with clear, up‐to‐date
and practical guidance on the management of thrombotic thrombocytopenic purpura (TTP) …

B cell depletion in the treatment of multiple sclerosis

KM Myhr, Ø Torkildsen, A Lossius, L Bø… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous
system. The latest development of B-cell depletion by anti-CD20 monoclonal antibodies has …

Ofatumumab for multirelapsing membranous nephropathy complicated by rituximab-induced serum-sickness

MA Podestà, B Ruggiero, G Remuzzi… - … Case Reports CP, 2020 - casereports.bmj.com
Rituximab (375 mg/m2) achieved remission of the first episode and six relapses of nephrotic
syndrome (NS) in a young male patient with podocyte phospholipase A2 receptor (PLA2R) …

Anti-rituximab antibodies in pediatric steroid-dependent nephrotic syndrome

Q Bertrand, S Mignot, T Kwon, A Couderc, A Maisin… - Pediatric …, 2022 - Springer
Background Rituximab is a chimeric anti-CD20 monoclonal antibody that induces sustained
remission in children with steroid-dependent nephrotic syndrome. However, there is no …

The use of obinutuzumab and ofatumumab in the treatment of immune thrombotic thrombocytopenic purpura

AJ Doyle, MJ Stubbs, W Lester… - British journal of …, 2022 - Wiley Online Library
Rituximab, an anti‐CD20 monoclonal antibody, can be used to treat immune thrombotic
thrombocytopenic purpura (iTTP) during acute presentation or disease relapse. Undesirable …

Unresponsive thrombotic thrombocytopenic purpura (TTP): challenges and solutions

V Lemiale, S Valade, E Mariotte - Therapeutics and Clinical Risk …, 2021 - Taylor & Francis
Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy secondary to a
severely decreased A Disintegrin And Metalloprotease with ThromboSpondin type 1 repeats …

[HTML][HTML] Therapeutic effects of rituximab combined with cyclophosphamide on refractory idiopathic thrombocytopenic purpura

J Wang, B Wang, Z Sun, K Xue - Experimental and …, 2019 - spandidos-publications.com
Therapeutic effects of rituximab combined with cyclophosphamide on refractory idiopathic
thrombocytopenic purpura (ITP) were investigated. We retrospectively analyzed 249 patients …

Management of acquired, immune thrombocytopenic purpura (iTTP): beyond the acute phase

JP Westwood, M Scully - Therapeutic Advances in …, 2022 - journals.sagepub.com
Modern therapy for acute TTP has resulted in a dramatic improvement in outcomes, with the
combination of plasma exchange, immunosuppression, and caplacizumab being associated …