Immune tolerance of tissue-engineered skin produced with allogeneic or xenogeneic fibroblasts and syngeneic keratinocytes grafted on mice
B Goyer, D Larouche, DH Kim, N Veillette, V Pruneau… - Acta Biomaterialia, 2019 - Elsevier
Organs are needed for the long-term replacement of diseased or wounded tissues. Various
technologies based on cells seeded in synthetic or biomaterial scaffolds, or scaffold-free …
technologies based on cells seeded in synthetic or biomaterial scaffolds, or scaffold-free …
[HTML][HTML] Inhibition of protein geranylgeranylation and farnesylation protects against graft-versus-host disease via effects on CD4 effector T cells
AK Hechinger, K Maas, C Dürr, F Leonhardt… - …, 2013 - ncbi.nlm.nih.gov
Despite advances in immunosuppressive regimens, acute graft-versus-host disease
remains a frequent complication of allogeneic hematopoietic cell transplantation …
remains a frequent complication of allogeneic hematopoietic cell transplantation …
Transplantation of tail skin to study allogeneic CD4 T cell responses in mice
M Schmaler, MAS Broggi… - Journal of Visualized …, 2014 - pmc.ncbi.nlm.nih.gov
The study of T cell responses and their consequences during allo-antigen recognition
requires a model that enables one to distinguish between donor and host T cells, to easily …
requires a model that enables one to distinguish between donor and host T cells, to easily …
Farnesyltransferase-inhibitors exert in vitro immunosuppressive capacity by inhibiting human B-cells
S Xu, S Dolff, N Mülling, HS Bachmann… - Frontiers in …, 2023 - frontiersin.org
Objectives Farnesyltransferase inhibitors (FTI), which inhibit the prenylation of Ras
GTPases, were developed as anti-cancer drugs. As additional target proteins for prenylation …
GTPases, were developed as anti-cancer drugs. As additional target proteins for prenylation …
The farnesyltransferase inhibitor tipifarnib protects against autoimmune hepatitis induced by Concanavalin A
J Guo, K Shirozu, T Akahoshi, Y Mizuta… - International …, 2020 - Elsevier
No effective treatment has been established for autoimmune hepatitis (AIH), except for liver
transplantation in the fatal stage. Little is known about the roles and mechanisms of …
transplantation in the fatal stage. Little is known about the roles and mechanisms of …
[PDF][PDF] Hemmung verschiedener intrazellulärer Signalwege in Immunzellen zur Reduzierung der akuten Transplantat gegen Wirt-Erkrankung
AK Hechinger - 2013 - freidok.uni-freiburg.de
Ein Organismus ist täglich einer Vielzahl von Krankheitserregern ausgesetzt, die durch das
Immunsystem größtenteils erfolgreich bekämpft werden können. Die größte …
Immunsystem größtenteils erfolgreich bekämpft werden können. Die größte …
[引用][C] Special patient populations: Transplant recipients
H Holdaas, JA Kobashigawa, B Fellstrøm, AG Jardine - Clinical lipidology, 2015 - Elsevier