Amygdala, neuropeptides, and chronic pain-related affective behaviors
Neuropeptides play important modulatory roles throughout the nervous system, functioning
as direct effectors or as interacting partners with other neuropeptide and neurotransmitter …
as direct effectors or as interacting partners with other neuropeptide and neurotransmitter …
Nicotine withdrawal
I McLaughlin, JA Dani, M De Biasi - The Neuropharmacology of Nicotine …, 2015 - Springer
An aversive abstinence syndrome manifests 4–24 h following cessation of chronic use of
nicotine-containing products. Symptoms peak on approximately the 3rd day and taper off …
nicotine-containing products. Symptoms peak on approximately the 3rd day and taper off …
The role of the central amygdala in alcohol dependence
Alcohol dependence is a chronically relapsing disorder characterized by compulsive drug-
seeking and drug-taking, loss of control in limiting intake, and the emergence of a …
seeking and drug-taking, loss of control in limiting intake, and the emergence of a …
VTA CRF neurons mediate the aversive effects of nicotine withdrawal and promote intake escalation
Dopaminergic neurons in the ventral tegmental area (VTA) are well known for mediating the
positive reinforcing effects of drugs of abuse. Here we identify in rodents and humans a …
positive reinforcing effects of drugs of abuse. Here we identify in rodents and humans a …
Alcohol and pain: a translational review of preclinical and clinical findings to inform future treatment strategies
Alcohol use disorder (AUD) and chronic pain are enduring and devastating conditions that
share an intersecting epidemiology and neurobiology. Chronic alcohol use itself can …
share an intersecting epidemiology and neurobiology. Chronic alcohol use itself can …
Chronic alcohol induced mechanical allodynia by promoting neuroinflammation: a mouse model of alcohol‐evoked neuropathic pain
V Borgonetti, AJ Roberts, M Bajo… - British Journal of …, 2023 - Wiley Online Library
Abstract Background and Purpose Chronic pain is considered a key factor contributing to
alcohol use disorder (AUD). The mechanisms responsible for chronic pain associated with …
alcohol use disorder (AUD). The mechanisms responsible for chronic pain associated with …
Nicotine e-cigarette vapor inhalation effects on nicotine & cotinine plasma levels and somatic withdrawal signs in adult male Wistar rats
C Montanari, LK Kelley, TM Kerr, M Cole… - Psychopharmacology, 2020 - Springer
Rationale Non-contingent chronic nicotine exposure procedures have evolved rapidly in
recent years, culminating in electronic nicotine delivery systems (ENDS or e-cigarettes) to …
recent years, culminating in electronic nicotine delivery systems (ENDS or e-cigarettes) to …
The Sigma-2 receptor/transmembrane protein 97 (σ2R/TMEM97) modulator JVW-1034 reduces heavy alcohol drinking and associated pain states in male mice
SG Quadir, SM Tanino, CD Rohl, JJ Sahn, EJ Yao… - …, 2021 - Elsevier
Abstract Alcohol Use Disorder (AUD) is a chronic relapsing disorder characterized by
compulsive alcohol intake, loss of control over alcohol intake, and a negative emotional …
compulsive alcohol intake, loss of control over alcohol intake, and a negative emotional …
Validation of a nicotine vapor self-administration model in rats with relevance to electronic cigarette use
The debate about electronic cigarettes is dividing healthcare professionals, policymakers,
manufacturers, and communities. A key limitation in our understanding of the cause and …
manufacturers, and communities. A key limitation in our understanding of the cause and …
Effect of chronic vapor nicotine exposure on affective and cognitive behavior in male mice
Nicotine use is a leading cause of preventable deaths worldwide, and most of those who
attempt to quit will relapse. While electronic cigarettes and other electronic nicotine delivery …
attempt to quit will relapse. While electronic cigarettes and other electronic nicotine delivery …