Understanding the pathophysiology of depression: From monoamines to the neurogenesis hypothesis model-are we there yet?
E Jesulola, P Micalos, IJ Baguley - Behavioural brain research, 2018 - Elsevier
A number of factors (biogenic amine deficiency, genetic, environmental, immunologic,
endocrine factors and neurogenesis) have been identified as mechanisms which provide …
endocrine factors and neurogenesis) have been identified as mechanisms which provide …
The neurobiology of depression and antidepressant action
P Willner, J Scheel-Krüger, C Belzung - Neuroscience & biobehavioral …, 2013 - Elsevier
We present a comprehensive overview of the neurobiology of unipolar major depression
and antidepressant drug action, integrating data from affective neuroscience, neuro-and …
and antidepressant drug action, integrating data from affective neuroscience, neuro-and …
Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group
The pattern of structural brain alterations associated with major depressive disorder (MDD)
remains unresolved. This is in part due to small sample sizes of neuroimaging studies …
remains unresolved. This is in part due to small sample sizes of neuroimaging studies …
Structural neuroimaging studies in major depressive disorder: meta-analysis and comparison with bipolar disorder
MJ Kempton, Z Salvador, MR Munafò… - Archives of general …, 2011 - jamanetwork.com
Context Although differences in clinical characteristics exist between major depressive
disorder (MDD) and bipolar disorder (BD), consistent structural brain abnormalities that …
disorder (MDD) and bipolar disorder (BD), consistent structural brain abnormalities that …
Magnetic resonance imaging studies in unipolar depression: systematic review and meta-regression analyses
Previous meta-analyses of structural MRI studies have shown diffuse cortical and sub-
cortical abnormalities in unipolar depression. However, the presence of duplicate …
cortical abnormalities in unipolar depression. However, the presence of duplicate …
Prenatal maternal depression alters amygdala functional connectivity in 6-month-old infants
A Qiu, TT Anh, Y Li, H Chen, A Rifkin-Graboi… - Translational …, 2015 - nature.com
Prenatal maternal depression is associated with alterations in the neonatal amygdala
microstructure, shedding light on the timing for the influence of prenatal maternal depression …
microstructure, shedding light on the timing for the influence of prenatal maternal depression …
Mapping the depressed brain: a meta-analysis of structural and functional alterations in major depressive disorder
BACKGROUND: Depression has a lifetime prevalence of up to 20%. Neuroimaging methods
have revealed various structural and functional changes that occur in a human brain during …
have revealed various structural and functional changes that occur in a human brain during …
Hippocampal atrophy in first episode depression: a meta-analysis of magnetic resonance imaging studies
BACKGROUND: Reduced hippocampal volume has been consistently observed in major
depressive disorder. Hippocampal volume loss is particularly evident in patients with …
depressive disorder. Hippocampal volume loss is particularly evident in patients with …
Fetal and infant outcomes in the offspring of parents with perinatal mental disorders: earliest influences
Mental illness is highly prevalent and runs in families. Mental disorders are considered to
enhance the risk for the development of psychopathology in the offspring. This heightened …
enhance the risk for the development of psychopathology in the offspring. This heightened …
Amygdala-ventral pallidum pathway decreases dopamine activity after chronic mild stress in rats
Background Major depressive disorder affects more than 15% of the population across their
lifespan. In this study, we used the well-characterized unpredictable chronic mild stress …
lifespan. In this study, we used the well-characterized unpredictable chronic mild stress …