Reprogrammed metabolism is a hallmark of cancer. However, the metabolic dependency of
cancer, from tumour initiation through disease progression and therapy resistance, requires …

The tumor microenvironment (TME) is a complex and ever-changing “rogue organ”
composed of its own blood supply, lymphatic and nervous systems, stroma, immune cells …

Aberrant metabolism is a major hallmark of cancer. Abnormal cancer metabolism, such as
aerobic glycolysis and increased anabolic pathways, has important roles in tumorigenesis …

High lipid content and excellent CO 2 fixation capability of microalgae by photosynthesis
have made microalgal biodiesel (BD) a promising carbon-neutral fuel. Nonetheless, the …

Cellular metabolism is at the foundation of all biological activities. The catabolic processes
that support cellular bioenergetics and survival have been well studied. By contrast, how …

One of the key challenges in cancer research is how to effectively kill cancer cells while
leaving the healthy cells intact. Cancer cells often have defects in cell death executioner …

De novo lipogenesis (DNL) is a complex and highly regulated process in which
carbohydrates from circulation are converted into fatty acids that are then used for …

Breast cancer is one of the most common malignancy among women worldwide. Metastasis
is mainly responsible for treatment failure and is the cause of most breast cancer deaths …

Rationale: Malignant ascites in peritoneal metastases is a lipid-enriched microenvironment
and is frequently involved in the poor prognosis of epithelial ovarian cancer (EOC) …

One of the most important metabolic hallmarks of cancer cells is deregulation of lipid
metabolism. In addition, enhancing de novo fatty acid (FA) synthesis, increasing lipid uptake …