[HTML][HTML] Principles and advances in ultrafast photoacoustics; applications to imaging cell mechanics and to probing cell nanostructure

B Audoin - Photoacoustics, 2023 - Elsevier
In this article we first present the foundations of ultrafast photoacoustics, a technique where
the acoustic wavelength in play can be considerably shorter than the optical wavelength …

[HTML][HTML] Nano-scientific application of atomic force microscopy in pathology: from molecules to tissues

TM Kiio, S Park - International Journal of Medical Sciences, 2020 - ncbi.nlm.nih.gov
The advantages of atomic force microscopy (AFM) in biological research are its high
imaging resolution, sensitivity, and ability to operate in physiological conditions. Over the …

Classification of cancer cells at the sub-cellular level by phonon microscopy using deep learning

F Pérez-Cota, G Martínez-Arellano, S La Cavera III… - Scientific Reports, 2023 - nature.com
There is a consensus about the strong correlation between the elasticity of cells and tissue
and their normal, dysplastic, and cancerous states. However, developments in cell …

Phonon imaging in 3D with a fibre probe

S La Cavera III, F Pérez-Cota, RJ Smith… - Light: Science & …, 2021 - nature.com
We show for the first time that a single ultrasonic imaging fibre is capable of simultaneously
accessing 3D spatial information and mechanical properties from microscopic objects. The …

Changes in intra-nuclear mechanics in response to DNA damaging agents revealed by time-domain Brillouin micro-spectroscopy

L Liu, M Simon, G Muggiolu, F Vilotte, M Antoine… - Photoacoustics, 2022 - Elsevier
How DNA damage and repair processes affect the biomechanical properties of the nucleus
interior remains unknown. Here, an opto-acoustic microscope based on time-domain …

3D phonon microscopy with sub-micron axial-resolution

RJ Smith, F Pérez-Cota, L Marques, M Clark - Scientific Reports, 2021 - nature.com
Brillouin light scattering (BLS) is an emerging method for cell imaging and characterisation.
It allows elasticity-related contrast, optical resolution and label-free operation. Phonon …

Perspective on non-invasive and non-destructive photoacoustic and photothermal applications

C Glorieux - Journal of Applied Physics, 2022 - pubs.aip.org
This contribution intends to convince readers that by virtue of the rich physics involved,
optical excitation, thermal diffusion, thermal expansion, and acoustic wave propagation, and …

High-sensitivity pump-probe spectroscopy with<? pag\break?> a dual-comb laser and a PM-Andi supercontinuum

C Gruber, J Pupeikis, SL Camenzind, B Willenberg… - Optics Letters, 2024 - opg.optica.org
Amplifier-based pump-probe systems, while versatile, often suffer from complexity and low
measurement speeds, especially when probing samples require low excitation fluences. To …

Time-domain feature extraction for target specificity in photoacoustic remote sensing microscopy

N Pellegrino, BR Ecclestone, D Dinakaran… - Optics Letters, 2022 - opg.optica.org
Photoacoustic remote sensing (PARS) microscopy is an emerging label-free optical
absorption imaging modality. PARS operates by capturing nanosecond-scale optical …

Brillouin spectroscopy for accurate assessment of morphological and mechanical characteristics in micro-structured samples

AA Passeri, C Argentati, F Morena… - Journal of Physics …, 2024 - iopscience.iop.org
Brillouin spectroscopy has recently attracted attention as a powerful tool for the
characterisation of the mechanical properties of heterogeneous materials, particularly in the …