Although cell-lineage and differentiation models dominate tumour classification and
treatment, the recognition that cancer is also a genomic disease has prompted a …

Childhood tumors containing cells that are morphologically and functionally similar to
normal progenitor cells provide fertile ground for investigating the links between …

We describe a method for automatic detection of absolute segmental copy numbers and
genotype status in complex cancer genome profiles measured with single-nucleotide …

Massive loss of valuable plant species in the past centuries and its adverse impact on
environmental and socioeconomic values has triggered the conservation of plant resources …

A highly sensitive and specific colorimetry-based rolling circle amplification (RCA) assay
method for single-nucleotide polymorphism genotyping has been developed. A circular …

Background: Preeclampsia (PE) is a syndromic disorder that affects 2% to 8% of
pregnancies and is diagnosed principally when hypertension appears in the second-d half …

OMICS technologies are relatively new biomarker discovery tools that can be applied to
study large sets of biological molecules. Their application in human observational studies …

Over the years, methods of cytogenetic analysis evolved and became part of routine
laboratory testing, providing valuable diagnostic and prognostic information in hematologic …

In this work, we developed a simple and accurate peptide nucleic acid (PNA)-based
sandwich hybridization assay for single nucleotide polymorphisms (SNPs) in the p53 gene …

In the era of personalized medicine, high-throughput technologies have allowed the
investigation of genetic variations underlying the inter-individual variability in drug …