Over the past several decades, the incidence of bacterial meningitis in children has decreased but there remains a significant burden of disease in adults, with a mortality of up …
B Wahl, KL O'Brien, A Greenbaum… - The Lancet Global …, 2018 - thelancet.com
Background Pneumococcal conjugate vaccine (PCV) and Haemophilus influenzae type b (Hib) vaccine are now used in most countries. To monitor global and regional progress …
SN Ladhani, S Collins, A Djennad… - The Lancet Infectious …, 2018 - thelancet.com
Summary Background Pneumococcal conjugate vaccines (PCVs) have substantially reduced the incidence of invasive pneumococcal disease caused by vaccine serotypes; …
Fungi must meet four criteria to infect humans: growth at human body temperatures, circumvention or penetration of surface barriers, lysis and absorption of tissue, and …
G Falkenhorst, C Remschmidt, T Harder… - PLoS …, 2017 - journals.plos.org
Background Routine vaccination of elderly people against pneumococcal diseases is recommended in many countries. National guidelines differ, recommending either the 23 …
HL Platt, JF Cardona, M Haranaka, HI Schwartz… - Vaccine, 2022 - Elsevier
Abstract Background Pneumococcal conjugate vaccines (PCVs) have greatly reduced the incidence of pneumococcal disease, yet unmet medical need remains due to increased …
T Shiri, S Datta, J Madan, A Tsertsvadze… - The Lancet Global …, 2017 - thelancet.com
Background The full extent to which childhood pneumococcal conjugate vaccines (PCV) can indirectly reduce illness in unvaccinated populations is not known. We aimed to estimate the …
G Hanquet, P Krizova, P Valentiner-Branth… - Thorax, 2019 - thorax.bmj.com
Background Pneumococcal conjugate vaccines (PCVs) have the potential to prevent pneumococcal disease through direct and indirect protection. This multicentre European …
JA Lewnard, WP Hanage - The Lancet Infectious Diseases, 2019 - thelancet.com
Serotype replacement in invasive pneumococcal disease threatens to undermine the most costly vaccination programme currently undertaken. However, the effects of replacement on …