Serotype distribution of Streptococcus pneumoniae causing invasive disease in children in the post-PCV era: A systematic review and meta-analysis

E Balsells, L Guillot, H Nair, MH Kyaw - PloS one, 2017 - journals.plos.org
Background Routine immunisation with pneumococcal conjugate vaccines (PCV7/10/13)
has reduced invasive pneumococcal disease (IPD) due to vaccine serotypes significantly …

Acute bacterial meningitis in adults

F McGill, RS Heyderman, S Panagiotou, AR Tunkel… - The Lancet, 2016 - thelancet.com
Over the past several decades, the incidence of bacterial meningitis in children has
decreased but there remains a significant burden of disease in adults, with a mortality of up …

Burden of Streptococcus pneumoniae and Haemophilus influenzae type b disease in children in the era of conjugate vaccines: global, regional, and national …

B Wahl, KL O'Brien, A Greenbaum… - The Lancet Global …, 2018 - thelancet.com
Background Pneumococcal conjugate vaccine (PCV) and Haemophilus influenzae type b
(Hib) vaccine are now used in most countries. To monitor global and regional progress …

Rapid increase in non-vaccine serotypes causing invasive pneumococcal disease in England and Wales, 2000–17: a prospective national observational cohort study

SN Ladhani, S Collins, A Djennad… - The Lancet Infectious …, 2018 - thelancet.com
Summary Background Pneumococcal conjugate vaccines (PCVs) have substantially
reduced the incidence of invasive pneumococcal disease caused by vaccine serotypes; …

Fungi that infect humans

JR Köhler, B Hube, R Puccia, A Casadevall… - Microbiology …, 2017 - Am Soc Microbiol
Fungi must meet four criteria to infect humans: growth at human body temperatures,
circumvention or penetration of surface barriers, lysis and absorption of tissue, and …

Effectiveness of the 23-valent pneumococcal polysaccharide vaccine (PPV23) against pneumococcal disease in the elderly: systematic review and meta-analysis

G Falkenhorst, C Remschmidt, T Harder… - PLoS …, 2017 - journals.plos.org
Background Routine vaccination of elderly people against pneumococcal diseases is
recommended in many countries. National guidelines differ, recommending either the 23 …

[HTML][HTML] A phase 3 trial of safety, tolerability, and immunogenicity of V114, 15-valent pneumococcal conjugate vaccine, compared with 13-valent pneumococcal …

HL Platt, JF Cardona, M Haranaka, HI Schwartz… - Vaccine, 2022 - Elsevier
Abstract Background Pneumococcal conjugate vaccines (PCVs) have greatly reduced the
incidence of pneumococcal disease, yet unmet medical need remains due to increased …

Indirect effects of childhood pneumococcal conjugate vaccination on invasive pneumococcal disease: a systematic review and meta-analysis

T Shiri, S Datta, J Madan, A Tsertsvadze… - The Lancet Global …, 2017 - thelancet.com
Background The full extent to which childhood pneumococcal conjugate vaccines (PCV) can
indirectly reduce illness in unvaccinated populations is not known. We aimed to estimate the …

Effect of childhood pneumococcal conjugate vaccination on invasive disease in older adults of 10 European countries: implications for adult vaccination

G Hanquet, P Krizova, P Valentiner-Branth… - Thorax, 2019 - thorax.bmj.com
Background Pneumococcal conjugate vaccines (PCVs) have the potential to prevent
pneumococcal disease through direct and indirect protection. This multicentre European …

Making sense of differences in pneumococcal serotype replacement

JA Lewnard, WP Hanage - The Lancet Infectious Diseases, 2019 - thelancet.com
Serotype replacement in invasive pneumococcal disease threatens to undermine the most
costly vaccination programme currently undertaken. However, the effects of replacement on …