Current understanding of natural antibodies and exploring the possibilities of modulation using veterinary models. A review
GIJ Reyneveld, HFJ Savelkoul… - Frontiers in …, 2020 - frontiersin.org
Natural antibodies (NAb) are defined as germline encoded immunoglobulins found in
individuals without (known) prior antigenic experience. NAb bind exogenous (eg, bacterial) …
individuals without (known) prior antigenic experience. NAb bind exogenous (eg, bacterial) …
Dietary phytochemicals as epigenetic modifiers in cancer: Promise and challenges
The influence of diet and environment on human health has been known since ages. Plant-
derived natural bioactive compounds (phytochemicals) have acquired an important role in …
derived natural bioactive compounds (phytochemicals) have acquired an important role in …
Exosomes harbor B cell targets in pancreatic adenocarcinoma and exert decoy function against complement-mediated cytotoxicity
Although B cell response is frequently found in cancer, there is little evidence that it alters
tumor development or progression. The process through which tumor-associated antigens …
tumor development or progression. The process through which tumor-associated antigens …
Methylglyoxal–an emerging biomarker for diabetes mellitus diagnosis and its detection methods
LR Bhat, S Vedantham, UM Krishnan… - Biosensors and …, 2019 - Elsevier
Diabetes Mellitus (DM) is one among the supreme metabolic issues observed in history
since 3000 BCE and has gained much interest recently due to the increasing number of …
since 3000 BCE and has gained much interest recently due to the increasing number of …
Leveraging histone glycation for cancer diagnostics and therapeutics
Cancer cells undergo metabolic reprogramming to rely mostly on aerobic glycolysis (the
Warburg effect). The increased glycolytic intake enhances the intracellular levels of reactive …
Warburg effect). The increased glycolytic intake enhances the intracellular levels of reactive …
Recent advances in histone glycation: emerging role in diabetes and cancer
Ever increasing information on genome and proteome has offered fascinating details and
new opportunities to understand the molecular biology. It is now known that histone proteins …
new opportunities to understand the molecular biology. It is now known that histone proteins …
The in vivo and in vitro approaches for establishing a link between advanced glycation end products and lung cancer
Advanced glycation end products (AGEs) are directly related to third aging‐associated
diseases, such as cardiovascular diseases, arteriosclerosis, and neurodegeneration …
diseases, such as cardiovascular diseases, arteriosclerosis, and neurodegeneration …
Glycation, oxidation and glycoxidation of IgG: a biophysical, biochemical, immunological and hematological study
Glycation and oxidation induce structural alterations in the proteins in an interdependent
manner with consequent pathological implications. The published literature presents wide …
manner with consequent pathological implications. The published literature presents wide …
Neo-epitopes on methylglyoxal modified human serum albumin lead to aggressive autoimmune response in diabetes
Glyco-oxidation of proteins has implications in the progression of diabetes type 2. Human
serum albumin is prone to glyco-oxidative attack by sugars and methylglyoxal being a strong …
serum albumin is prone to glyco-oxidative attack by sugars and methylglyoxal being a strong …
Glycation, nitro-oxidation and glyco-nitro-oxidation of human serum albumin: A physico-chemical study
A Tarannum, Z Arif, K Alam - Journal of Molecular Structure, 2020 - Elsevier
Glycation and nitro-oxidation influences proteins' structure/conformation in an inter-
connected manner with subsequent pathological implications. Modified human serum …
connected manner with subsequent pathological implications. Modified human serum …